O'Neill E - Search Results

1

TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.

Eyres M, Lanfredini S, Xu H, Burns A, Blake A, Willenbrock F, Goldin R, Hughes D, Hughes S, Thapa A, Vavoulis D, Hubert A, D'Costa Z, Sabbagh A, Abraham AG, Blancher C, Jones S, Verrill C, Silva M, Soonawalla Z, Maughan T, Schuh A, Mukherjee S, O'Neill E. Eyres M, et al. Gastroenterology. 2021 Aug;161(2):653-668.e16. doi: 10.1053/j.gastro.2021.04.044. Epub 2021 Apr 27. Gastroenterology. 2021. PMID: 33915173

2

Predicting Early Disease Recurrence of Pancreatic Cancer following Surgery: Determining the Role of NUDT15 as a Prognostic Biomarker.

Hughes DL, Willenbrock F, Soonawalla Z, Mukherjee S, O'Neill E. Hughes DL, et al. Curr Oncol. 2022 Apr 6;29(4):2516-2529. doi: 10.3390/curroncol29040206. Curr Oncol. 2022. PMID: 35448180 Free PMC article.

3

Circulating biomarkers and outcomes from a randomised phase 2 trial of gemcitabine versus capecitabine-based chemoradiotherapy for pancreatic cancer.

Willenbrock F, Cox CM, Parkes EE, Wilhelm-Benartzi CS, Abraham AG, Owens R, Sabbagh A, Jones CM, Hughes DLI, Maughan T, Hurt CN, O'Neill EE, Mukherjee S. Willenbrock F, et al. Br J Cancer. 2021 Feb;124(3):581-586. doi: 10.1038/s41416-020-01120-z. Epub 2020 Oct 26. Br J Cancer. 2021. PMID: 33100327 Free PMC article. Clinical Trial.

4

RAS in pancreatic cancer.

Lanfredini S, Thapa A, O'Neill E. Lanfredini S, et al. Biochem Soc Trans. 2019 Aug 30;47(4):961-972. doi: 10.1042/BST20170521. Epub 2019 Jul 24. Biochem Soc Trans. 2019. PMID: 31341034 Review.

5

The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma.

Wang LM, Silva MA, D'Costa Z, Bockelmann R, Soonawalla Z, Liu S, O'Neill E, Mukherjee S, McKenna WG, Muschel R, Fokas E. Wang LM, et al. Oncotarget. 2016 Jan 26;7(4):4183-94. doi: 10.18632/oncotarget.6770. Oncotarget. 2016. PMID: 26716653 Free PMC article.

6

⁸⁹Zr-anti-γH2AX-TAT but not ¹⁸F-FDG Allows Early Monitoring of Response to Chemotherapy in a Mouse Model of Pancreatic Ductal Adenocarcinoma.

Knight JC, Mosley MJ, Bravo LC, Kersemans V, Allen PD, Mukherjee S, O'Neill E, Cornelissen B. Knight JC, et al. Clin Cancer Res. 2017 Nov 1;23(21):6498-6504. doi: 10.1158/1078-0432.CCR-17-0664. Epub 2017 Aug 3. Clin Cancer Res. 2017. PMID: 28774899

7

Pancreatic ductal adenocarcinoma: From genetics to biology to radiobiology to oncoimmunology and all the way back to the clinic.

Fokas E, O'Neill E, Gordon-Weeks A, Mukherjee S, McKenna WG, Muschel RJ. Fokas E, et al. Biochim Biophys Acta. 2015 Jan;1855(1):61-82. doi: 10.1016/j.bbcan.2014.12.001. Epub 2014 Dec 7. Biochim Biophys Acta. 2015. PMID: 25489989 Review.

8

Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.

D'Costa Z, Jones K, Azad A, van Stiphout R, Lim SY, Gomes AL, Kinchesh P, Smart SC, Gillies McKenna W, Buffa FM, Sansom OJ, Muschel RJ, O'Neill E, Fokas E. D'Costa Z, et al. Cancer Res. 2017 Nov 1;77(21):5952-5962. doi: 10.1158/0008-5472.CAN-16-2833. Epub 2017 Aug 1. Cancer Res. 2017. PMID: 28765154

9

Dynamic Physiological Culture of Ex Vivo Human Tissue: A Systematic Review.

Hughes DL, Hughes A, Soonawalla Z, Mukherjee S, O'Neill E. Hughes DL, et al. Cancers (Basel). 2021 Jun 8;13(12):2870. doi: 10.3390/cancers13122870. Cancers (Basel). 2021. PMID: 34201273 Free PMC article. Review.

10

PI3K/Akt-mediated regulation of p53 in cancer.

Abraham AG, O'Neill E. Abraham AG, et al. Biochem Soc Trans. 2014 Aug;42(4):798-803. doi: 10.1042/BST20140070. Biochem Soc Trans. 2014. PMID: 25109960 Review.

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