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Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease.
J Virol. 2023 Feb 28;97(2):e0167222. doi: 10.1128/jvi.01672-22. Epub 2023 Jan 18.
J Virol. 2023.
PMID: 36651748
Free PMC article.
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.
Minikel EV, Zhao HT, Le J, O'Moore J, Pitstick R, Graffam S, Carlson GA, Kavanaugh MP, Kriz J, Kim JB, Ma J, Wille H, Aiken J, McKenzie D, Doh-Ura K, Beck M, O'Keefe R, Stathopoulos J, Caron T, Schreiber SL, Carroll JB, Kordasiewicz HB, Cabin DE, Vallabh SM.
Minikel EV, et al. Among authors: o moore j.
Nucleic Acids Res. 2020 Nov 4;48(19):10615-10631. doi: 10.1093/nar/gkaa616.
Nucleic Acids Res. 2020.
PMID: 32776089
Free PMC article.
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Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNS.
Mortberg MA, Zhao HT, Reidenbach AG, Gentile JE, Kuhn E, O'Moore J, Dooley PM, Connors TR, Mazur C, Allen SW, Trombetta BA, McManus A, Moore MR, Liu J, Cabin DE, Kordasiewicz HB, Mathews J, Arnold SE, Vallabh SM, Minikel EV.
Mortberg MA, et al. Among authors: o moore j.
JCI Insight. 2022 Mar 22;7(6):e156532. doi: 10.1172/jci.insight.156532.
JCI Insight. 2022.
PMID: 35133987
Free PMC article.
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Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy.
Graham DL, Gray AJ, Joyce JA, Yu D, O'Moore J, Carlson GA, Shearman MS, Dellovade TL, Hering H.
Graham DL, et al. Among authors: o moore j.
Neuropharmacology. 2014 Apr;79:307-13. doi: 10.1016/j.neuropharm.2013.11.025. Epub 2013 Dec 8.
Neuropharmacology. 2014.
PMID: 24326295
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Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400.
Cameron A, Giacomozzi B, Joyce J, Gray A, Graham D, Ousson S, Neny M, Beher D, Carlson G, O'Moore J, Shearman M, Hering H.
Cameron A, et al. Among authors: o moore j.
FEBS Lett. 2013 Nov 15;587(22):3722-8. doi: 10.1016/j.febslet.2013.09.042. Epub 2013 Oct 7.
FEBS Lett. 2013.
PMID: 24113653
Free article.
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The claw paw mutation reveals a role for Lgi4 in peripheral nerve development.
Bermingham JR Jr, Shearin H, Pennington J, O'Moore J, Jaegle M, Driegen S, van Zon A, Darbas A, Ozkaynak E, Ryu EJ, Milbrandt J, Meijer D.
Bermingham JR Jr, et al. Among authors: o moore j.
Nat Neurosci. 2006 Jan;9(1):76-84. doi: 10.1038/nn1598. Epub 2005 Dec 11.
Nat Neurosci. 2006.
PMID: 16341215
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