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Page 1
Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity.
O'Mara AE, Johnson JW, Linderman JD, Brychta RJ, McGehee S, Fletcher LA, Fink YA, Kapuria D, Cassimatis TM, Kelsey N, Cero C, Sater ZA, Piccinini F, Baskin AS, Leitner BP, Cai H, Millo CM, Dieckmann W, Walter M, Javitt NB, Rotman Y, Walter PJ, Ader M, Bergman RN, Herscovitch P, Chen KY, Cypess AM. O'Mara AE, et al. J Clin Invest. 2020 May 1;130(5):2209-2219. doi: 10.1172/JCI131126. J Clin Invest. 2020. PMID: 31961826 Free PMC article. Clinical Trial.
Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist.
Baskin AS, Linderman JD, Brychta RJ, McGehee S, Anflick-Chames E, Cero C, Johnson JW, O'Mara AE, Fletcher LA, Leitner BP, Duckworth CJ, Huang S, Cai H, Garraffo HM, Millo CM, Dieckmann W, Tolstikov V, Chen EY, Gao F, Narain NR, Kiebish MA, Walter PJ, Herscovitch P, Chen KY, Cypess AM. Baskin AS, et al. Among authors: o mara ae. Diabetes. 2018 Oct;67(10):2113-2125. doi: 10.2337/db18-0462. Epub 2018 Jul 6. Diabetes. 2018. PMID: 29980535 Free PMC article. Clinical Trial.
Sexual Dimorphisms in Adult Human Brown Adipose Tissue.
Fletcher LA, Kim K, Leitner BP, Cassimatis TM, O'Mara AE, Johnson JW, Halprin MS, McGehee SM, Brychta RJ, Cypess AM, Chen KY. Fletcher LA, et al. Among authors: o mara ae. Obesity (Silver Spring). 2020 Feb;28(2):241-246. doi: 10.1002/oby.22698. Obesity (Silver Spring). 2020. PMID: 31970907 Free PMC article.
Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity.
Chen KY, Brychta RJ, Abdul Sater Z, Cassimatis TM, Cero C, Fletcher LA, Israni NS, Johnson JW, Lea HJ, Linderman JD, O'Mara AE, Zhu KY, Cypess AM. Chen KY, et al. Among authors: o mara ae. J Biol Chem. 2020 Feb 14;295(7):1926-1942. doi: 10.1074/jbc.REV119.007363. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914415 Free PMC article. Review.