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Targeting the IL-6/JAK/STAT3 signalling axis in cancer.
Johnson DE, O'Keefe RA, Grandis JR. Johnson DE, et al. Among authors: o keefe ra. Nat Rev Clin Oncol. 2018 Apr;15(4):234-248. doi: 10.1038/nrclinonc.2018.8. Epub 2018 Feb 6. Nat Rev Clin Oncol. 2018. PMID: 29405201 Free PMC article. Review.
Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer.
Brand TM, Hartmann S, Bhola NE, Li H, Zeng Y, O'Keefe RA, Ranall MV, Bandyopadhyay S, Soucheray M, Krogan NJ, Kemp C, Duvvuri U, LaVallee T, Johnson DE, Ozbun MA, Bauman JE, Grandis JR. Brand TM, et al. Among authors: o keefe ra. Cancer Res. 2018 May 1;78(9):2383-2395. doi: 10.1158/0008-5472.CAN-17-1672. Epub 2018 Feb 12. Cancer Res. 2018. PMID: 29440171 Free PMC article.
Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer.
Bouhaddou M, Lee RH, Li H, Bhola NE, O'Keefe RA, Naser M, Zhu TR, Nwachuku K, Duvvuri U, Olshen AB, Roy R, Hechmer A, Bolen J, Keysar SB, Jimeno A, Mills GB, Vandenberg S, Swaney DL, Johnson DE, Krogan NJ, Grandis JR. Bouhaddou M, et al. Among authors: o keefe ra. JCI Insight. 2021 Oct 22;6(20):e151982. doi: 10.1172/jci.insight.151982. JCI Insight. 2021. PMID: 34546978 Free PMC article.
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.
Swaney DL, Ramms DJ, Wang Z, Park J, Goto Y, Soucheray M, Bhola N, Kim K, Zheng F, Zeng Y, McGregor M, Herrington KA, O'Keefe R, Jin N, VanLandingham NK, Foussard H, Von Dollen J, Bouhaddou M, Jimenez-Morales D, Obernier K, Kreisberg JF, Kim M, Johnson DE, Jura N, Grandis JR, Gutkind JS, Ideker T, Krogan NJ. Swaney DL, et al. Science. 2021 Oct;374(6563):eabf2911. doi: 10.1126/science.abf2911. Epub 2021 Oct 1. Science. 2021. PMID: 34591642 Free PMC article.
Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer.
Brand TM, Hartmann S, Bhola NE, Li H, Zeng Y, O'Keefe RA, Ranall MV, Bandyopadhyay S, Soucheray M, Krogan NJ, Kemp C, Duvvuri U, LaVallee T, Johnson DE, Ozbun MA, Bauman JE, Grandis JR. Brand TM, et al. Among authors: o keefe ra. Cancer Res. 2022 Sep 2;82(17):3188. doi: 10.1158/0008-5472.CAN-22-1307. Cancer Res. 2022. PMID: 36052495 No abstract available.
Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer.
Brand TM, Hartmann S, Bhola NE, Li H, Zeng Y, O'Keefe RA, Ranall MV, Bandyopadhyay S, Soucheray M, Krogan NJ, Kemp C, Duvvuri U, LaVallee T, Johnson DE, Ozbun MA, Bauman JE, Grandis JR. Brand TM, et al. Among authors: o keefe ra. Cancer Res. 2022 Sep 2;82(17):3187. doi: 10.1158/0008-5472.CAN-22-1308. Cancer Res. 2022. PMID: 36052496 No abstract available.
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