O'Hara S - Search Results

1

Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis.

Loarca L, De Assuncao TM, Jalan-Sakrikar N, Bronk S, Krishnan A, Huang B, Morton L, Trussoni C, Bonilla LM, Krueger E, O'Hara S, Splinter P, Shi G, Pisarello MJL, Gores GJ, Huebert RC, LaRusso NF. Loarca L, et al. Lab Invest. 2017 Nov;97(11):1385-1396. doi: 10.1038/labinvest.2017.63. Epub 2017 Sep 11. Lab Invest. 2017. PMID: 28892096 Free PMC article.

2

Apical organelle discharge by Cryptosporidium parvum is temperature, cytoskeleton, and intracellular calcium dependent and required for host cell invasion.

Chen XM, O'Hara SP, Huang BQ, Nelson JB, Lin JJ, Zhu G, Ward HD, LaRusso NF. Chen XM, et al. Infect Immun. 2004 Dec;72(12):6806-16. doi: 10.1128/IAI.72.12.6806-6816.2004. Infect Immun. 2004. PMID: 15557601 Free PMC article.

3

Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion.

Chen XM, O'Hara SP, Huang BQ, Splinter PL, Nelson JB, LaRusso NF. Chen XM, et al. Proc Natl Acad Sci U S A. 2005 May 3;102(18):6338-43. doi: 10.1073/pnas.0408563102. Epub 2005 Apr 25. Proc Natl Acad Sci U S A. 2005. PMID: 15851691 Free PMC article.

4

Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-kappaB.

Chen XM, O'Hara SP, Nelson JB, Splinter PL, Small AJ, Tietz PS, Limper AH, LaRusso NF. Chen XM, et al. J Immunol. 2005 Dec 1;175(11):7447-56. doi: 10.4049/jimmunol.175.11.7447. J Immunol. 2005. PMID: 16301652

5

Distribution of Cryptosporidium parvum sporozoite apical organelles during attachment to and internalization by cultured biliary epithelial cells.

O'Hara SP, Huang BQ, Chen XM, Nelson J, LaRusso NF. O'Hara SP, et al. J Parasitol. 2005 Oct;91(5):995-9. doi: 10.1645/GE-495R.1. J Parasitol. 2005. PMID: 16419739

6

Cryptosporidium parvum infects human cholangiocytes via sphingolipid-enriched membrane microdomains.

Nelson JB, O'Hara SP, Small AJ, Tietz PS, Choudhury AK, Pagano RE, Chen XM, LaRusso NF. Nelson JB, et al. Cell Microbiol. 2006 Dec;8(12):1932-45. doi: 10.1111/j.1462-5822.2006.00759.x. Epub 2006 Jul 18. Cell Microbiol. 2006. PMID: 16848787 Free PMC article.

7

The human immunodeficiency virus type 1 tat protein enhances Cryptosporidium parvum-induced apoptosis in cholangiocytes via a Fas ligand-dependent mechanism.

O'Hara SP, Small AJ, Nelson JB, Badley AD, Chen XM, Gores GJ, Larusso NF. O'Hara SP, et al. Infect Immun. 2007 Feb;75(2):684-96. doi: 10.1128/IAI.01348-06. Epub 2006 Nov 21. Infect Immun. 2007. PMID: 17118988 Free PMC article.

8

A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection.

Chen XM, Splinter PL, O'Hara SP, LaRusso NF. Chen XM, et al. J Biol Chem. 2007 Sep 28;282(39):28929-28938. doi: 10.1074/jbc.M702633200. Epub 2007 Jul 27. J Biol Chem. 2007. PMID: 17660297 Free PMC article.

9

The immunobiology of cholangiocytes.

Chen XM, O'Hara SP, LaRusso NF. Chen XM, et al. Immunol Cell Biol. 2008 Aug-Sep;86(6):497-505. doi: 10.1038/icb.2008.37. Epub 2008 May 27. Immunol Cell Biol. 2008. PMID: 18504452 Free PMC article. Review.

10

Host cell actin remodeling in response to Cryptosporidium.

O'Hara SP, Small AJ, Chen XM, LaRusso NF. O'Hara SP, et al. Subcell Biochem. 2008;47:92-100. doi: 10.1007/978-0-387-78267-6_7. Subcell Biochem. 2008. PMID: 18512344 Review.

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