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Closing the tau loop: the missing tau mutation.
McCarthy A, Lonergan R, Olszewska DA, O'Dowd S, Cummins G, Magennis B, Fallon EM, Pender N, Huey ED, Cosentino S, O'Rourke K, Kelly BD, O'Connell M, Delon I, Farrell M, Spillantini MG, Rowland LP, Fahn S, Craig P, Hutton M, Lynch T. McCarthy A, et al. Brain. 2015 Oct;138(Pt 10):3100-9. doi: 10.1093/brain/awv234. Epub 2015 Aug 21. Brain. 2015. PMID: 26297556 Free PMC article.
The ELISA-measured increase in cerebrospinal fluid tau that discriminates Alzheimer's disease from other neurodegenerative disorders is not attributable to differential recognition of tau assembly forms.
O'Dowd ST, Ardah MT, Johansson P, Lomakin A, Benedek GB, Roberts KA, Cummins G, El Agnaf OM, Svensson J, Zetterberg H, Lynch T, Walsh DM. O'Dowd ST, et al. J Alzheimers Dis. 2013;33(4):923-8. doi: 10.3233/JAD-2012-121393. J Alzheimers Dis. 2013. PMID: 23034520
Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.
Iovino M, Agathou S, González-Rueda A, Del Castillo Velasco-Herrera M, Borroni B, Alberici A, Lynch T, O'Dowd S, Geti I, Gaffney D, Vallier L, Paulsen O, Káradóttir RT, Spillantini MG. Iovino M, et al. Brain. 2015 Nov;138(Pt 11):3345-59. doi: 10.1093/brain/awv222. Epub 2015 Jul 27. Brain. 2015. PMID: 26220942 Free PMC article.
Fluctuating cognition in the Lewy body dementias.
O'Dowd S, Schumacher J, Burn DJ, Bonanni L, Onofrj M, Thomas A, Taylor JP. O'Dowd S, et al. Brain. 2019 Nov 1;142(11):3338-3350. doi: 10.1093/brain/awz235. Brain. 2019. PMID: 31411317 Review.
48 results