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Schizophrenia.
Kahn RS, Sommer IE, Murray RM, Meyer-Lindenberg A, Weinberger DR, Cannon TD, O'Donovan M, Correll CU, Kane JM, van Os J, Insel TR. Kahn RS, et al. Nat Rev Dis Primers. 2015 Nov 12;1:15067. doi: 10.1038/nrdp.2015.67. Nat Rev Dis Primers. 2015. PMID: 27189524 Review.
Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.
Williams NM, Green EK, Macgregor S, Dwyer S, Norton N, Williams H, Raybould R, Grozeva D, Hamshere M, Zammit S, Jones L, Cardno A, Kirov G, Jones I, O'Donovan MC, Owen MJ, Craddock N. Williams NM, et al. Arch Gen Psychiatry. 2006 Apr;63(4):366-73. doi: 10.1001/archpsyc.63.4.366. Arch Gen Psychiatry. 2006. PMID: 16585465
Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples.
Talkowski ME, Seltman H, Bassett AS, Brzustowicz LM, Chen X, Chowdari KV, Collier DA, Cordeiro Q, Corvin AP, Deshpande SN, Egan MF, Gill M, Kendler KS, Kirov G, Heston LL, Levitt P, Lewis DA, Li T, Mirnics K, Morris DW, Norton N, O'Donovan MC, Owen MJ, Richard C, Semwal P, Sobell JL, St Clair D, Straub RE, Thelma BK, Vallada H, Weinberger DR, Williams NM, Wood J, Zhang F, Devlin B, Nimgaonkar VL. Talkowski ME, et al. Biol Psychiatry. 2006 Jul 15;60(2):152-62. doi: 10.1016/j.biopsych.2006.02.015. Epub 2006 Apr 21. Biol Psychiatry. 2006. PMID: 16631129 Free PMC article. Review.
Neurexin 1 (NRXN1) deletions in schizophrenia.
Kirov G, Rujescu D, Ingason A, Collier DA, O'Donovan MC, Owen MJ. Kirov G, et al. Schizophr Bull. 2009 Sep;35(5):851-4. doi: 10.1093/schbul/sbp079. Epub 2009 Aug 12. Schizophr Bull. 2009. PMID: 19675094 Free PMC article. Review. No abstract available.
Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.
Ikeda M, Tomita Y, Mouri A, Koga M, Okochi T, Yoshimura R, Yamanouchi Y, Kinoshita Y, Hashimoto R, Williams HJ, Takeda M, Nakamura J, Nabeshima T, Owen MJ, O'Donovan MC, Honda H, Arinami T, Ozaki N, Iwata N. Ikeda M, et al. Biol Psychiatry. 2010 Feb 1;67(3):263-9. doi: 10.1016/j.biopsych.2009.08.030. Epub 2009 Oct 22. Biol Psychiatry. 2010. PMID: 19850283 Clinical Trial.
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia.
Ingason A, Giegling I, Cichon S, Hansen T, Rasmussen HB, Nielsen J, Jürgens G, Muglia P, Hartmann AM, Strengman E, Vasilescu C, Mühleisen TW, Djurovic S, Melle I, Lerer B, Möller HJ, Francks C, Pietiläinen OP, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Walshe M, Vassos E, Di Forti M, Murray R, Bonetto C, Tosato S; GROUP Investigators; Cantor RM, Rietschel M, Craddock N, Owen MJ, Peltonen L, Andreassen OA, Nöthen MM, St Clair D, Ophoff RA, O'Donovan MC, Collier DA, Werge T, Rujescu D. Ingason A, et al. Hum Mol Genet. 2010 Apr 1;19(7):1379-86. doi: 10.1093/hmg/ddq009. Epub 2010 Jan 12. Hum Mol Genet. 2010. PMID: 20071346 Free PMC article.
Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia.
Walters JT, Corvin A, Owen MJ, Williams H, Dragovic M, Quinn EM, Judge R, Smith DJ, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Moskvina V, Dwyer S, O'Donoghue T, Morar B, Cooper M, Chandler D, Jablensky A, Gill M, Kaladjieva L, Morris DW, O'Donovan MC, Rujescu D, Donohoe G. Walters JT, et al. Arch Gen Psychiatry. 2010 Jul;67(7):692-700. doi: 10.1001/archgenpsychiatry.2010.81. Arch Gen Psychiatry. 2010. PMID: 20603450
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.
Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O'Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V, Straub RE, Weinberger DR, O'Neill FA, Walsh D, Bronstein M, Darvasi A, Lencz T, Malhotra AK, Rujescu D, Giegling I, Werge T, Hansen T, Ingason A, Nöethen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Cantor RM, Ophoff R, Corvin A, Morris DW, Gill M, Pato CN, Pato MT, Macedo A, Gurling HM, McQuillin A, Pimm J, Hultman C, Lichtenstein P, Sklar P, Purcell SM, Scolnick E, St Clair D, Blackwood DH, Kendler KS; GROUP investigators; International Schizophrenia Consortium. Chen X, et al. Mol Psychiatry. 2011 Nov;16(11):1117-29. doi: 10.1038/mp.2010.96. Epub 2010 Sep 14. Mol Psychiatry. 2011. PMID: 20838396 Free PMC article.
Neurodevelopmental hypothesis of schizophrenia.
Owen MJ, O'Donovan MC, Thapar A, Craddock N. Owen MJ, et al. Br J Psychiatry. 2011 Mar;198(3):173-5. doi: 10.1192/bjp.bp.110.084384. Br J Psychiatry. 2011. PMID: 21357874 Free PMC article.
1,280 results