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PANX3 Channels Regulate Architecture, Adhesion, Barrier Function, and Inflammation in the Skin.
J Invest Dermatol. 2023 Aug;143(8):1509-1519.e14. doi: 10.1016/j.jid.2023.01.030. Epub 2023 Feb 21.
J Invest Dermatol. 2023.
PMID: 36813158
Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells.
Freeman TJ, Sayedyahossein S, Johnston D, Sanchez-Pupo RE, O'Donnell B, Huang K, Lakhani Z, Nouri-Nejad D, Barr KJ, Harland L, Latosinsky S, Grant A, Dagnino L, Penuela S.
Freeman TJ, et al.
Cancers (Basel). 2019 Jan 16;11(1):102. doi: 10.3390/cancers11010102.
Cancers (Basel). 2019.
PMID: 30654593
Free PMC article.
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Double deletion of Panx1 and Panx3 affects skin and bone but not hearing.
Abitbol JM, O'Donnell BL, Wakefield CB, Jewlal E, Kelly JJ, Barr K, Willmore KE, Allman BL, Penuela S.
Abitbol JM, et al. Among authors: o donnell bl.
J Mol Med (Berl). 2019 May;97(5):723-736. doi: 10.1007/s00109-019-01779-9. Epub 2019 Mar 27.
J Mol Med (Berl). 2019.
PMID: 30918989
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Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein.
Nouri-Nejad D, O'Donnell BL, Patil CS, Sanchez-Pupo RE, Johnston D, Sayedyahossein S, Jurcic K, Lau R, Gyenis L, Litchfield DW, Jackson MF, Gloor GB, Penuela S.
Nouri-Nejad D, et al. Among authors: o donnell bl.
Mol Biol Cell. 2021 Mar 1;32(5):376-390. doi: 10.1091/mbc.E19-10-0585. Epub 2021 Jan 6.
Mol Biol Cell. 2021.
PMID: 33405952
Free PMC article.
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Pannexin 3 channels in health and disease.
O'Donnell BL, Penuela S.
O'Donnell BL, et al.
Purinergic Signal. 2021 Dec;17(4):577-589. doi: 10.1007/s11302-021-09805-7. Epub 2021 Jul 12.
Purinergic Signal. 2021.
PMID: 34250568
Free PMC article.
Review.
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Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner.
Wakefield CB, Lee VR, Johnston D, Boroumand P, Pillon NJ, Sayedyahossein S, O'Donnell BL, Tang J, Sanchez-Pupo RE, Barr KJ, Gros R, Flynn L, Borradaile NM, Klip A, Beier F, Penuela S.
Wakefield CB, et al. Among authors: o donnell bl.
Int J Obes (Lond). 2022 Apr;46(4):726-738. doi: 10.1038/s41366-021-01037-4. Epub 2021 Dec 13.
Int J Obes (Lond). 2022.
PMID: 34897286
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Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes.
Sanchez-Pupo RE, O'Donnell BL, Johnston D, Gyenis L, Litchfield DW, Penuela S.
Sanchez-Pupo RE, et al. Among authors: o donnell bl.
Mol Biol Cell. 2022 Mar 1;33(3):ar24. doi: 10.1091/mbc.E21-08-0387. Epub 2022 Jan 5.
Mol Biol Cell. 2022.
PMID: 34985913
Free PMC article.
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Skin in the game: pannexin channels in healthy and cancerous skin.
O'Donnell BL, Penuela S.
O'Donnell BL, et al.
Biochem J. 2023 Dec 13;480(23):1929-1949. doi: 10.1042/BCJ20230176.
Biochem J. 2023.
PMID: 38038973
Review.
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