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151 results

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Page 1
Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis.
Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, Daly MJ, Broman KW, Lander ES, Nadeau JH. Shao H, et al. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19910-4. doi: 10.1073/pnas.0810388105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066216 Free PMC article.
Novel lethal mouse mutants produced in balancer chromosome screens.
Hentges KE, Nakamura H, Furuta Y, Yu Y, Thompson DM, O'Brien W, Bradley A, Justice MJ. Hentges KE, et al. Gene Expr Patterns. 2006 Aug;6(6):653-65. doi: 10.1016/j.modgep.2005.11.015. Epub 2006 Feb 8. Gene Expr Patterns. 2006. PMID: 16466971
Requirement of argininosuccinate lyase for systemic nitric oxide production.
Erez A, Nagamani SC, Shchelochkov OA, Premkumar MH, Campeau PM, Chen Y, Garg HK, Li L, Mian A, Bertin TK, Black JO, Zeng H, Tang Y, Reddy AK, Summar M, O'Brien WE, Harrison DG, Mitch WE, Marini JC, Aschner JL, Bryan NS, Lee B. Erez A, et al. Among authors: o brien we. Nat Med. 2011 Nov 13;17(12):1619-26. doi: 10.1038/nm.2544. Nat Med. 2011. PMID: 22081021 Free PMC article.
Phenylbutyrate improves nitrogen disposal via an alternative pathway without eliciting an increase in protein breakdown and catabolism in control and ornithine transcarbamylase-deficient patients.
Marini JC, Lanpher BC, Scaglia F, O'Brien WE, Sun Q, Garlick PJ, Jahoor F, Lee B. Marini JC, et al. Among authors: o brien we. Am J Clin Nutr. 2011 Jun;93(6):1248-54. doi: 10.3945/ajcn.110.009043. Epub 2011 Apr 13. Am J Clin Nutr. 2011. PMID: 21490144 Free PMC article. Clinical Trial.
Double-blind therapeutic trial in Angelman syndrome using betaine and folic acid.
Peters SU, Bird LM, Kimonis V, Glaze DG, Shinawi LM, Bichell TJ, Barbieri-Welge R, Nespeca M, Anselm I, Waisbren S, Sanborn E, Sun Q, O'Brien WE, Beaudet AL, Bacino CA. Peters SU, et al. Among authors: o brien we. Am J Med Genet A. 2010 Aug;152A(8):1994-2001. doi: 10.1002/ajmg.a.33509. Am J Med Genet A. 2010. PMID: 20635355 Free PMC article. Clinical Trial.
151 results