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Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. Svensson MND, et al. Among authors: nygaard g. Sci Adv. 2020 Jun 26;6(26):eaba4353. doi: 10.1126/sciadv.aba4353. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32637608 Free PMC article.
Caspase-8 Variant G Regulates Rheumatoid Arthritis Fibroblast-Like Synoviocyte Aggressive Behavior.
Ansalone C, Ainsworth RI, Nygaard G, Ai R, Prideaux EB, Hammaker D, Perumal NB, Weichert K, Tung F, Kodandapani L, Sauder JM, Mertsching EC, Benschop RJ, Boyle DL, Wang W, Firestein GS. Ansalone C, et al. Among authors: nygaard g. ACR Open Rheumatol. 2022 Apr;4(4):288-299. doi: 10.1002/acr2.11384. Epub 2021 Dec 28. ACR Open Rheumatol. 2022. PMID: 34963199 Free PMC article.
Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function.
Ainsworth RI, Hammaker D, Nygaard G, Ansalone C, Machado C, Zhang K, Zheng L, Carrillo L, Wildberg A, Kuhs A, Svensson MND, Boyle DL, Firestein GS, Wang W. Ainsworth RI, et al. Among authors: nygaard g. Nat Commun. 2022 Oct 20;13(1):6221. doi: 10.1038/s41467-022-33785-w. Nat Commun. 2022. PMID: 36266270 Free PMC article.
63 results