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A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Andersen OM, Bøgh N, Landau AM, Pløen GG, Jensen AMG, Monti G, Ulhøi BP, Nyengaard JR, Jacobsen KR, Jørgensen MM, Holm IE, Kristensen ML, Alstrup AKO, Hansen ESS, Teunissen CE, Breidenbach L, Droescher M, Liu Y, Pedersen HS, Callesen H, Luo Y, Bolund L, Brooks DJ, Laustsen C, Small SA, Mikkelsen LF, Sørensen CB. Andersen OM, et al. Among authors: nyengaard jr. Cell Rep Med. 2022 Sep 20;3(9):100740. doi: 10.1016/j.xcrm.2022.100740. Epub 2022 Sep 12. Cell Rep Med. 2022. PMID: 36099918 Free PMC article.
Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.
Fjorback AW, Seaman M, Gustafsen C, Mehmedbasic A, Gokool S, Wu C, Militz D, Schmidt V, Madsen P, Nyengaard JR, Willnow TE, Christensen EI, Mobley WB, Nykjær A, Andersen OM. Fjorback AW, et al. Among authors: nyengaard jr. J Neurosci. 2012 Jan 25;32(4):1467-80. doi: 10.1523/JNEUROSCI.2272-11.2012. J Neurosci. 2012. PMID: 22279231 Free PMC article.
TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice.
Reinert LS, Harder L, Holm CK, Iversen MB, Horan KA, Dagnæs-Hansen F, Ulhøi BP, Holm TH, Mogensen TH, Owens T, Nyengaard JR, Thomsen AR, Paludan SR. Reinert LS, et al. Among authors: nyengaard jr. J Clin Invest. 2012 Apr;122(4):1368-76. doi: 10.1172/JCI60893. Epub 2012 Mar 19. J Clin Invest. 2012. PMID: 22426207 Free PMC article.
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Glerup S, Lume M, Olsen D, Nyengaard JR, Vaegter CB, Gustafsen C, Christensen EI, Kjolby M, Hay-Schmidt A, Bender D, Madsen P, Saarma M, Nykjaer A, Petersen CM. Glerup S, et al. Among authors: nyengaard jr. Cell Rep. 2013 Jan 31;3(1):186-99. doi: 10.1016/j.celrep.2012.12.011. Epub 2013 Jan 17. Cell Rep. 2013. PMID: 23333276 Free article.
SORLA Expression in Synaptic Plexiform Layers of Mouse Retina.
Monti G, Jensen ML, Mehmedbasic A, Jørgensen MM, Holm IE, Barkholt P, Zole E, Vægter CB, Vorum H, Nyengaard JR, Andersen OM. Monti G, et al. Among authors: nyengaard jr. Mol Neurobiol. 2020 Jul;57(7):3106-3117. doi: 10.1007/s12035-020-01946-x. Epub 2020 May 29. Mol Neurobiol. 2020. PMID: 32472518
376 results