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2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Bernhart E, Kogelnik N, Prasch J, Gottschalk B, Goeritzer M, Depaoli MR, Reicher H, Nusshold C, Plastira I, Hammer A, Fauler G, Malli R, Graier WF, Malle E, Sattler W. Bernhart E, et al. Among authors: nusshold c. Redox Biol. 2018 May;15:441-451. doi: 10.1016/j.redox.2018.01.003. Epub 2018 Jan 5. Redox Biol. 2018. PMID: 29413957 Free PMC article.
Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro.
Nusshold C, Kollroser M, Köfeler H, Rechberger G, Reicher H, Ullen A, Bernhart E, Waltl S, Kratzer I, Hermetter A, Hackl H, Trajanoski Z, Hrzenjak A, Malle E, Sattler W. Nusshold C, et al. Free Radic Biol Med. 2010 Jun 15;48(12):1588-600. doi: 10.1016/j.freeradbiomed.2010.02.037. Epub 2010 Mar 11. Free Radic Biol Med. 2010. PMID: 20226853 Free PMC article.
Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin.
Üllen A, Nusshold C, Glasnov T, Saf R, Cantillo D, Eibinger G, Reicher H, Fauler G, Bernhart E, Hallstrom S, Kogelnik N, Zangger K, Oliver Kappe C, Malle E, Sattler W. Üllen A, et al. Among authors: nusshold c. Biochem Pharmacol. 2015 Feb 15;93(4):470-81. doi: 10.1016/j.bcp.2014.12.017. Epub 2015 Jan 6. Biochem Pharmacol. 2015. PMID: 25576489 Free PMC article.
Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.
Bernhart E, Damm S, Wintersperger A, Nusshold C, Brunner AM, Plastira I, Rechberger G, Reicher H, Wadsack C, Zimmer A, Malle E, Sattler W. Bernhart E, et al. Among authors: nusshold c. Biochem Pharmacol. 2015 Jul 15;96(2):119-30. doi: 10.1016/j.bcp.2015.05.007. Epub 2015 May 19. Biochem Pharmacol. 2015. PMID: 26002572 Free PMC article.
Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Nusshold C, Üllen A, Kogelnik N, Bernhart E, Reicher H, Plastira I, Glasnov T, Zangger K, Rechberger G, Kollroser M, Fauler G, Wolinski H, Weksler BB, Romero IA, Kohlwein SD, Couraud PO, Malle E, Sattler W. Nusshold C, et al. Free Radic Biol Med. 2016 Jan;90:59-74. doi: 10.1016/j.freeradbiomed.2015.11.010. Epub 2015 Nov 11. Free Radic Biol Med. 2016. PMID: 26577177 Free PMC article.
Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture.
Bernhart E, Kollroser M, Rechberger G, Reicher H, Heinemann A, Schratl P, Hallström S, Wintersperger A, Nusshold C, DeVaney T, Zorn-Pauly K, Malli R, Graier W, Malle E, Sattler W. Bernhart E, et al. Among authors: nusshold c. Proteomics. 2010 Jan;10(1):141-58. doi: 10.1002/pmic.200900195. Proteomics. 2010. PMID: 19899077 Free PMC article.
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