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TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.
Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, Kiemeney LA, Mariette X, Richard-Miceli C, Canhão H, Fonseca JE, de Vries N, Tak PP, Crusius JB, Nurmohamed MT, Kurreeman F, Mikuls TR, Okada Y, Stahl EA, Larson DE, Deluca TL, O'Laughlin M, Fronick CC, Fulton LL, Kosoy R, Ransom M, Bhangale TR, Ortmann W, Cagan A, Gainer V, Karlson EW, Kohane I, Murphy SN, Martin J, Zhernakova A, Klareskog L, Padyukov L, Worthington J, Mardis ER, Seldin MF, Gregersen PK, Behrens T, Raychaudhuri S, Denny JC, Plenge RM. Diogo D, et al. Among authors: nurmohamed mt. PLoS One. 2015 Apr 7;10(4):e0122271. doi: 10.1371/journal.pone.0122271. eCollection 2015. PLoS One. 2015. PMID: 25849893 Free PMC article.
Brief Report: The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis.
Cui J, Diogo D, Stahl EA, Canhao H, Mariette X, Greenberg JD, Okada Y, Pappas DA, Fulton RS, Tak PP, Nurmohamed MT, Lee A, Larson DE, Kurreeman F, Deluca TL, O'Laughlin M, Fronick CC, Fulton LL, Mardis ER, van der Horst-Bruinsma IE, Wolbink GJ, Gregersen PK, Kremer JM, Crusius JB, de Vries N, Huizinga TW, Fonseca JE, Miceli-Richard C, Karlson EW, Coenen MJ, Barton A, Plenge RM, Raychaudhuri S. Cui J, et al. Among authors: nurmohamed mt. Arthritis Rheumatol. 2017 Apr;69(4):735-741. doi: 10.1002/art.39966. Arthritis Rheumatol. 2017. PMID: 27788309 Free PMC article.
Using adalimumab serum concentration to choose a subsequent biological DMARD in rheumatoid arthritis patients failing adalimumab treatment (ADDORA-switch): study protocol for a fully blinded randomised superiority test-treatment trial.
Wientjes MHM, Atiqi S, Wolbink GJ, Nurmohamed MT, Boers M, Rispens T, de Vries A, van Vollenhoven RF, van den Bemt BJF, den Broeder AA. Wientjes MHM, et al. Among authors: nurmohamed mt. Trials. 2021 Jun 19;22(1):406. doi: 10.1186/s13063-021-05358-7. Trials. 2021. PMID: 34147123 Free PMC article.
NT-proBNP and sRAGE levels in early rheumatoid arthritis.
Heslinga M, Teunissen C, Agca R, van der Woude D, Huizinga T, van Laar J, den Broeder A, Lems W, Nurmohamed M. Heslinga M, et al. Scand J Rheumatol. 2023 May;52(3):243-249. doi: 10.1080/03009742.2022.2042975. Epub 2022 Mar 11. Scand J Rheumatol. 2023. PMID: 35274588
Low dose, add-on prednisolone in patients with rheumatoid arthritis aged 65+: the pragmatic randomised, double-blind placebo-controlled GLORIA trial.
Boers M, Hartman L, Opris-Belinski D, Bos R, Kok MR, Da Silva JA, Griep EN, Klaasen R, Allaart CF, Baudoin P, Raterman HG, Szekanecz Z, Buttgereit F, Masaryk P, Klausch LT, Paolino S, Schilder AM, Lems WF, Cutolo M; GLORIA Trial consortium. Boers M, et al. Ann Rheum Dis. 2022 Jul;81(7):925-936. doi: 10.1136/annrheumdis-2021-221957. Epub 2022 May 31. Ann Rheum Dis. 2022. PMID: 35641125 Free PMC article. Clinical Trial.
Rituximab dose-dependent infection risk in rheumatoid arthritis is not mediated through circulating immunoglobulins, neutrophils or B cells.
Opdam MAA, de Leijer JH, den Broeder N, Thurlings RM, van der Weele W, Nurmohamed MT, Kok MR, van Bon L, Ten Cate DF, Verhoef LM, den Broeder AA. Opdam MAA, et al. Among authors: nurmohamed mt. Rheumatology (Oxford). 2022 Dec 23;62(1):330-334. doi: 10.1093/rheumatology/keac318. Rheumatology (Oxford). 2022. PMID: 35686851
A meta-analysis of methotrexate polyglutamates in relation to efficacy and toxicity of methotrexate in inflammatory arthritis, colitis and dermatitis.
van de Meeberg MM, Hebing RCF, Nurmohamed MT, Fidder HH, Heymans MW, Bouma G, de Bruin-Weller MS, Tekstra J, van den Bemt B, de Jonge R, Bulatović Ćalasan M. van de Meeberg MM, et al. Among authors: nurmohamed mt. Br J Clin Pharmacol. 2023 Jan;89(1):61-79. doi: 10.1111/bcp.15579. Epub 2022 Nov 20. Br J Clin Pharmacol. 2023. PMID: 36326810 Free PMC article.
370 results