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Thymoquinone-rich fraction nanoemulsion (TQRFNE) decreases Aβ40 and Aβ42 levels by modulating APP processing, up-regulating IDE and LRP1, and down-regulating BACE1 and RAGE in response to high fat/cholesterol diet-induced rats.
Ismail N, Ismail M, Azmi NH, Bakar MFA, Yida Z, Abdullah MA, Basri H. Ismail N, et al. Among authors: azmi nh. Biomed Pharmacother. 2017 Nov;95:780-788. doi: 10.1016/j.biopha.2017.08.074. Epub 2017 Sep 8. Biomed Pharmacother. 2017. PMID: 28892789
Beneficial effects of TQRF and TQ nano- and conventional emulsions on memory deficit, lipid peroxidation, total antioxidant status, antioxidants genes expression and soluble Aβ levels in high fat-cholesterol diet-induced rats.
Ismail N, Ismail M, Azmi NH, Bakar MFA, Yida Z, Stanslas J, Sani D, Basri H, Abdullah MA. Ismail N, et al. Among authors: azmi nh. Chem Biol Interact. 2017 Sep 25;275:61-73. doi: 10.1016/j.cbi.2017.07.014. Epub 2017 Jul 20. Chem Biol Interact. 2017. PMID: 28734741
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