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Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanova T, Urzi C, Ge H, Geest GA, Bruggmann R, Djonov V, Nuoffer JM, Vermathen P, Zamboni N, Riether C, Ochsenbein A, Peng RW, Kocher GJ, Schmid RA, Dorn P, Marti TM. Deng H, et al. Among authors: nuoffer jm. Cell Mol Life Sci. 2022 Jul 25;79(8):445. doi: 10.1007/s00018-022-04453-5. Cell Mol Life Sci. 2022. PMID: 35877003 Free PMC article.
Elimination of chronic viral infection by blocking CD27 signaling.
Matter M, Odermatt B, Yagita H, Nuoffer JM, Ochsenbein AF. Matter M, et al. Among authors: nuoffer jm. J Exp Med. 2006 Sep 4;203(9):2145-55. doi: 10.1084/jem.20060651. Epub 2006 Aug 21. J Exp Med. 2006. PMID: 16923852 Free PMC article.
T cell inhibitory mechanisms in a model of aggressive Non-Hodgkin's Lymphoma.
Hilmenyuk T, Ruckstuhl CA, Hayoz M, Berchtold C, Nuoffer JM, Solanki S, Keun HC, Beavis PA, Riether C, Ochsenbein AF. Hilmenyuk T, et al. Among authors: nuoffer jm. Oncoimmunology. 2017 Sep 21;7(1):e1365997. doi: 10.1080/2162402X.2017.1365997. eCollection 2017. Oncoimmunology. 2017. PMID: 29296517 Free PMC article.
Argininosuccinate neurotoxicity and prevention by creatine in argininosuccinate lyase deficiency: An in vitro study in rat three-dimensional organotypic brain cell cultures.
Diez-Fernandez C, Hertig D, Loup M, Diserens G, Henry H, Vermathen P, Nuoffer JM, Häberle J, Braissant O. Diez-Fernandez C, et al. Among authors: nuoffer jm. J Inherit Metab Dis. 2019 Nov;42(6):1077-1087. doi: 10.1002/jimd.12090. Epub 2019 Apr 14. J Inherit Metab Dis. 2019. PMID: 30907007 Free article. Review.
ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics.
Liu H, He Z, Germič N, Ademi H, Frangež Ž, Felser A, Peng S, Riether C, Djonov V, Nuoffer JM, Bovet C, Mlinarič-Raščan I, Zlobec I, Fiedler M, Perren A, Simon HU. Liu H, et al. Among authors: nuoffer jm. Cell Death Differ. 2020 Jun;27(6):1965-1980. doi: 10.1038/s41418-019-0476-5. Epub 2019 Dec 16. Cell Death Differ. 2020. PMID: 31844253 Free PMC article.
115 results