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A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus.
Melin N, Yarahmadov T, Sanchez-Taltavull D, Birrer FE, Brodie TM, Petit B, Felser A, Nuoffer JM, Montani M, Vozenin MC, Herrmann E, Candinas D, Aebersold DM, Stroka D. Melin N, et al. Among authors: nuoffer jm. JHEP Rep. 2022 May 21;4(7):100508. doi: 10.1016/j.jhepr.2022.100508. eCollection 2022 Jul. JHEP Rep. 2022. PMID: 35712694 Free PMC article.
ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics.
Liu H, He Z, Germič N, Ademi H, Frangež Ž, Felser A, Peng S, Riether C, Djonov V, Nuoffer JM, Bovet C, Mlinarič-Raščan I, Zlobec I, Fiedler M, Perren A, Simon HU. Liu H, et al. Among authors: nuoffer jm. Cell Death Differ. 2020 Jun;27(6):1965-1980. doi: 10.1038/s41418-019-0476-5. Epub 2019 Dec 16. Cell Death Differ. 2020. PMID: 31844253 Free PMC article.
115 results