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Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration.
Nunes MJ, Carvalho AN, Reis J, Costa D, Moutinho M, Mateus J, Mendes de Almeida R, Brito S, Risso D, Nunes S, Castro-Caldas M, Gama MJ, Rodrigues CMP, Xapelli S, Diógenes MJ, Cartier N, Chali F, Piguet F, Rodrigues E. Nunes MJ, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):166993. doi: 10.1016/j.bbadis.2023.166993. Epub 2023 Dec 22. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38142760 Free article.
Comparative Chemical Profiling and Antimicrobial/Anticancer Evaluation of Extracts from Farmed versus Wild Agelas oroides and Sarcotragus foetidus Sponges.
Varamogianni-Mamatsi D, Nunes MJ, Marques V, Anastasiou TI, Kagiampaki E, Vernadou E, Dailianis T, Kalogerakis N, Branco LC, Rodrigues CMP, Sobral RG, Gaudêncio SP, Mandalakis M. Varamogianni-Mamatsi D, et al. Among authors: nunes mj. Mar Drugs. 2023 Nov 26;21(12):612. doi: 10.3390/md21120612. Mar Drugs. 2023. PMID: 38132933 Free PMC article.
NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease.
Caria I, Nunes MJ, Ciraci V, Carvalho AN, Ranito C, Santos SG, Gama MJ, Castro-Caldas M, Rodrigues CMP, Ruas JL, Rodrigues E. Caria I, et al. Among authors: nunes mj. Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166980. doi: 10.1016/j.bbadis.2023.166980. Epub 2023 Dec 5. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38061599 Free article.
Sustained PGC-1α2 or PGC-1α3 expression induces astrocyte dysfunction and degeneration.
Nunes MJ, Carvalho AN, Sá-Lemos C, Colaço M, Cervenka I, Ciraci V, Santos SG, Ribeiro MM, Castanheira M, Jannig PR, Gama MJ, Castro-Caldas M, Rodrigues CMP, Rodrigues E, Ruas JL. Nunes MJ, et al. Eur J Cell Biol. 2024 Mar;103(1):151377. doi: 10.1016/j.ejcb.2023.151377. Epub 2023 Nov 19. Eur J Cell Biol. 2024. PMID: 38006841 Free article.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
Expression of microRNAs miR-21 and miR-326 associated with HIF-1α regulation in neurospheres of glioblastoma submitted to ionizing radiation treatment.
Turra LP, Rodrigues AR, Neto FSL, Novais PC, Nunes MJ, Tirapelli VC, Peria FM, Carneiro VM, de Assis Cirino ML, Carlotti CG Jr, Tirapelli DPDC. Turra LP, et al. Among authors: nunes mj. Rep Pract Oncol Radiother. 2022 May 19;27(2):215-225. doi: 10.5603/RPOR.a2022.0040. eCollection 2022. Rep Pract Oncol Radiother. 2022. PMID: 36299385 Free PMC article.
46 results