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Page 1
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.
Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA. Chaurasia B, et al. Among authors: nunes cn. Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4. Science. 2019. PMID: 31273070 Free PMC article.
Lymphatic absorption, metabolism, and excretion of a therapeutic peptide in dogs and rats.
Zou Y, Bateman TJ, Adreani C, Shen X, Cunningham PK, Wang B, Trinh T, Christine A, Hong X, Nunes CN, Johnson CV, Zhang AS, Staskiewicz SJ, Braun M, Kumar S, Reddy VB. Zou Y, et al. Among authors: nunes cn. Drug Metab Dispos. 2013 Dec;41(12):2206-14. doi: 10.1124/dmd.113.051524. Epub 2013 Oct 2. Drug Metab Dispos. 2013. PMID: 24088325
Identification of receptors for neuromedin U and its role in feeding.
Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Williams DL Jr, Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q. Howard AD, et al. Among authors: nunes cn. Nature. 2000 Jul 6;406(6791):70-4. doi: 10.1038/35017610. Nature. 2000. PMID: 10894543
11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice.
Hermanowski-Vosatka A, Balkovec JM, Cheng K, Chen HY, Hernandez M, Koo GC, Le Grand CB, Li Z, Metzger JM, Mundt SS, Noonan H, Nunes CN, Olson SH, Pikounis B, Ren N, Robertson N, Schaeffer JM, Shah K, Springer MS, Strack AM, Strowski M, Wu K, Wu T, Xiao J, Zhang BB, Wright SD, Thieringer R. Hermanowski-Vosatka A, et al. Among authors: nunes cn. J Exp Med. 2005 Aug 15;202(4):517-27. doi: 10.1084/jem.20050119. J Exp Med. 2005. PMID: 16103409 Free PMC article.
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass.
Chen AS, Marsh DJ, Trumbauer ME, Frazier EG, Guan XM, Yu H, Rosenblum CI, Vongs A, Feng Y, Cao L, Metzger JM, Strack AM, Camacho RE, Mellin TN, Nunes CN, Min W, Fisher J, Gopal-Truter S, MacIntyre DE, Chen HY, Van der Ploeg LH. Chen AS, et al. Among authors: nunes cn. Nat Genet. 2000 Sep;26(1):97-102. doi: 10.1038/79254. Nat Genet. 2000. PMID: 10973258
Melanocortin mediated inhibition of feeding behavior in rats.
Murphy B, Nunes CN, Ronan JJ, Harper CM, Beall MJ, Hanaway M, Fairhurst AM, Van der Ploeg LH, MacIntyre DE, Mellin TN. Murphy B, et al. Among authors: nunes cn. Neuropeptides. 1998 Dec;32(6):491-7. doi: 10.1016/s0143-4179(98)90077-4. Neuropeptides. 1998. PMID: 9920446
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