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Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB. Preston S, et al. Among authors: nowell c. FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7. FASEB J. 2017. PMID: 28687609
., Cornaglia, M., McGee, S. L., Young, N. D., Davis, R. A., Crawford, S., Nowell, C., Ansell, B. R. E., Fisher, G. M., Andrews, K. T., Chang, B. C. H., Gijs, M. A. M., Sternberg, P. W., Auwerx, J., Baell, J., Hofmann, A., Jabbar, A., Gasser, R. ...
., Cornaglia, M., McGee, S. L., Young, N. D., Davis, R. A., Crawford, S., Nowell, C., Ansell, B. R. E., Fisher, G. M., Andrews …
Low cost whole-organism screening of compounds for anthelmintic activity.
Preston S, Jabbar A, Nowell C, Joachim A, Ruttkowski B, Baell J, Cardno T, Korhonen PK, Piedrafita D, Ansell BR, Jex AR, Hofmann A, Gasser RB. Preston S, et al. Among authors: nowell c. Int J Parasitol. 2015 Apr;45(5):333-43. doi: 10.1016/j.ijpara.2015.01.007. Epub 2015 Mar 5. Int J Parasitol. 2015. PMID: 25746136
Potential Toxicity of Polymyxins in Human Lung Epithelial Cells.
Ahmed MU, Velkov T, Lin YW, Yun B, Nowell CJ, Zhou F, Zhou QT, Chan K, Azad MAK, Li J. Ahmed MU, et al. Antimicrob Agents Chemother. 2017 May 24;61(6):e02690-16. doi: 10.1128/AAC.02690-16. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28416543 Free PMC article.
Stress hormone signaling through β-adrenergic receptors regulates macrophage mechanotype and function.
Kim TH, Ly C, Christodoulides A, Nowell CJ, Gunning PW, Sloan EK, Rowat AC. Kim TH, et al. Among authors: nowell cj. FASEB J. 2019 Mar;33(3):3997-4006. doi: 10.1096/fj.201801429RR. Epub 2018 Dec 3. FASEB J. 2019. PMID: 30509116 Free PMC article.
These findings show that through remodeling of the actin cytoskeleton, beta-AR-mediated stress hormone signaling modulates macrophage mechanotype to impact functions that play a critical role in immune response.-Kim, T.-H., Ly, C., Christodoulides, A., Nowell, C
These findings show that through remodeling of the actin cytoskeleton, beta-AR-mediated stress hormone signaling modulates macrophage mechan …
149 results