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The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain.
Charbonnel C, Niazi AK, Elvira-Matelot E, Nowak E, Zytnicki M, de Bures A, Jobet E, Opsomer A, Shamandi N, Nowotny M, Carapito C, Reichheld JP, Vaucheret H, Sáez-Vásquez J. Charbonnel C, et al. Among authors: nowak e. Nucleic Acids Res. 2017 Nov 16;45(20):11891-11907. doi: 10.1093/nar/gkx820. Nucleic Acids Res. 2017. PMID: 28981840 Free PMC article.
Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect.
Warminski M, Kowalska J, Nowak E, Kubacka D, Tibble R, Kasprzyk R, Sikorski PJ, Gross JD, Nowotny M, Jemielity J. Warminski M, et al. Among authors: nowak e. ACS Chem Biol. 2021 Feb 19;16(2):334-343. doi: 10.1021/acschembio.0c00864. Epub 2021 Jan 13. ACS Chem Biol. 2021. PMID: 33439620 Free PMC article.
mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.
Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J. Rydzik AM, et al. Among authors: nowak e. Nucleic Acids Res. 2017 Sep 6;45(15):8661-8675. doi: 10.1093/nar/gkx569. Nucleic Acids Res. 2017. PMID: 28666355 Free PMC article.
398 results