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5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure.
Janssen W, Schymura Y, Novoyatleva T, Kojonazarov B, Boehm M, Wietelmann A, Luitel H, Murmann K, Krompiec DR, Tretyn A, Pullamsetti SS, Weissmann N, Seeger W, Ghofrani HA, Schermuly RT. Janssen W, et al. Among authors: novoyatleva t. Biomed Res Int. 2015;2015:438403. doi: 10.1155/2015/438403. Epub 2015 Feb 1. Biomed Res Int. 2015. PMID: 25667920 Free PMC article.
Cardiac deletion of Smyd2 is dispensable for mouse heart development.
Diehl F, Brown MA, van Amerongen MJ, Novoyatleva T, Wietelmann A, Harriss J, Ferrazzi F, Böttger T, Harvey RP, Tucker PW, Engel FB. Diehl F, et al. Among authors: novoyatleva t. PLoS One. 2010 Mar 17;5(3):e9748. doi: 10.1371/journal.pone.0009748. PLoS One. 2010. PMID: 20305823 Free PMC article.
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction.
Novoyatleva T, Schymura Y, Janssen W, Strobl F, Swiercz JM, Patra C, Posern G, Wietelmann A, Zheng TS, Schermuly RT, Engel FB. Novoyatleva T, et al. Basic Res Cardiol. 2013 Mar;108(2):325. doi: 10.1007/s00395-012-0325-x. Epub 2013 Jan 17. Basic Res Cardiol. 2013. PMID: 23325387 Free PMC article.
Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis.
Sajjad A, Novoyatleva T, Vergarajauregui S, Troidl C, Schermuly RT, Tucker HO, Engel FB. Sajjad A, et al. Among authors: novoyatleva t. Biochim Biophys Acta. 2014 Nov;1843(11):2556-62. doi: 10.1016/j.bbamcr.2014.06.019. Epub 2014 Jul 8. Biochim Biophys Acta. 2014. PMID: 25014164 Free PMC article.
p38 MAPK Inhibition Improves Heart Function in Pressure-Loaded Right Ventricular Hypertrophy.
Kojonazarov B, Novoyatleva T, Boehm M, Happe C, Sibinska Z, Tian X, Sajjad A, Luitel H, Kriechling P, Posern G, Evans SM, Grimminger F, Ghofrani HA, Weissmann N, Bogaard HJ, Seeger W, Schermuly RT. Kojonazarov B, et al. Among authors: novoyatleva t. Am J Respir Cell Mol Biol. 2017 Nov;57(5):603-614. doi: 10.1165/rcmb.2016-0374OC. Am J Respir Cell Mol Biol. 2017. PMID: 28657795
ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension.
Budas GR, Boehm M, Kojonazarov B, Viswanathan G, Tian X, Veeroju S, Novoyatleva T, Grimminger F, Hinojosa-Kirschenbaum F, Ghofrani HA, Weissmann N, Seeger W, Liles JT, Schermuly RT. Budas GR, et al. Among authors: novoyatleva t. Am J Respir Crit Care Med. 2018 Feb 1;197(3):373-385. doi: 10.1164/rccm.201703-0502OC. Am J Respir Crit Care Med. 2018. PMID: 28910144
Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension.
Boehm M, Arnold N, Braithwaite A, Pickworth J, Lu C, Novoyatleva T, Kiely DG, Grimminger F, Ghofrani HA, Weissmann N, Seeger W, Lawrie A, Schermuly RT, Kojonazarov B. Boehm M, et al. Among authors: novoyatleva t. BMC Pulm Med. 2018 Mar 2;18(1):41. doi: 10.1186/s12890-018-0604-x. BMC Pulm Med. 2018. PMID: 29499691 Free PMC article.
Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding.
Rai N, Veeroju S, Schymura Y, Janssen W, Wietelmann A, Kojonazarov B, Weissmann N, Stasch JP, Ghofrani HA, Seeger W, Schermuly RT, Novoyatleva T. Rai N, et al. Among authors: novoyatleva t. Biomed Res Int. 2018 Jan 3;2018:3293584. doi: 10.1155/2018/3293584. eCollection 2018. Biomed Res Int. 2018. PMID: 29511676 Free PMC article.
38 results