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Immobility-associated thromboprotection is conserved across mammalian species from bear to human.
Thienel M, Müller-Reif JB, Zhang Z, Ehreiser V, Huth J, Shchurovska K, Kilani B, Schweizer L, Geyer PE, Zwiebel M, Novotny J, Lüsebrink E, Little G, Orban M, Nicolai L, El Nemr S, Titova A, Spannagl M, Kindberg J, Evans AL, Mach O, Vogel M, Tiedt S, Ormanns S, Kessler B, Dueck A, Friebe A, Jørgensen PG, Majzoub-Altweck M, Blutke A, Polzin A, Stark K, Kääb S, Maier D, Gibbins JM, Limper U, Frobert O, Mann M, Massberg S, Petzold T. Thienel M, et al. Among authors: novotny j. Science. 2023 Apr 14;380(6641):178-187. doi: 10.1126/science.abo5044. Epub 2023 Apr 13. Science. 2023. PMID: 37053338
Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation.
Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. Pircher J, et al. Among authors: novotny j. Nat Commun. 2018 Apr 18;9(1):1523. doi: 10.1038/s41467-018-03925-2. Nat Commun. 2018. PMID: 29670076 Free PMC article.
Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Novotny J, Chandraratne S, Weinberger T, Philippi V, Stark K, Ehrlich A, Pircher J, Konrad I, Oberdieck P, Titova A, Hoti Q, Schubert I, Legate KR, Urtz N, Lorenz M, Pelisek J, Massberg S, von Brühl ML, Schulz C. Novotny J, et al. PLoS One. 2018 Jan 2;13(1):e0190728. doi: 10.1371/journal.pone.0190728. eCollection 2018. PLoS One. 2018. PMID: 29293656 Free PMC article.
Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps.
Marx C, Novotny J, Salbeck D, Zellner KR, Nicolai L, Pekayvaz K, Kilani B, Stockhausen S, Bürgener N, Kupka D, Stocker TJ, Weckbach LT, Pircher J, Moser M, Joner M, Desmet W, Adriaenssens T, Neumann FJ, Gerschlick AH, Ten Berg JM, Lorenz M, Stark K. Marx C, et al. Among authors: novotny j. Blood. 2019 Nov 21;134(21):1859-1872. doi: 10.1182/blood.2019000518. Blood. 2019. PMID: 31481482 Free PMC article.
Thrombus NET content is associated with clinical outcome in stroke and myocardial infarction.
Novotny J, Oberdieck P, Titova A, Pelisek J, Chandraratne S, Nicol P, Hapfelmeier A, Joner M, Maegdefessel L, Poppert H, Pircher J, Massberg S, Friedrich B, Zimmer C, Schulz C, Boeckh-Behrens T. Novotny J, et al. Neurology. 2020 Jun 2;94(22):e2346-e2360. doi: 10.1212/WNL.0000000000009532. Epub 2020 May 20. Neurology. 2020. PMID: 32434865
Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium).
Joner M, Koppara T, Byrne RA, Castellanos MI, Lewerich J, Novotny J, Guagliumi G, Xhepa E, Adriaenssens T, Godschalk TC, Malik N, Alfonso F, Tada T, Neumann FJ, Desmet W, Ten Berg JM, Gershlick AH, Feldman LJ, Massberg S, Kastrati A; Prevention of PRESTIGE Investigators. Joner M, et al. Among authors: novotny j. JACC Cardiovasc Interv. 2018 Jul 23;11(14):1340-1350. doi: 10.1016/j.jcin.2018.02.029. JACC Cardiovasc Interv. 2018. PMID: 30025727 Free article.
COVID-19-associated Large Vessel Stroke in a 28-year-old Patient : NETs and Platelets Possible Key Players in Acute Thrombus Formation.
Boeckh-Behrens T, Golkowski D, Ikenberg B, Schlegel J, Protzer U, Schulz C, Novotny J, Kreiser K, Zimmer C, Hemmer B, Wunderlich S. Boeckh-Behrens T, et al. Among authors: novotny j. Clin Neuroradiol. 2021 Jun;31(2):511-514. doi: 10.1007/s00062-020-00992-1. Epub 2021 Jan 29. Clin Neuroradiol. 2021. PMID: 33512534 Free PMC article. No abstract available.
996 results