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TRPM7 kinase is required for insulin production and compensatory islet responses during obesity.
Khajavi N, Beck A, Riçku K, Beyerle P, Jacob K, Syamsul SF, Belkacemi A, Reinach PS, Schreier PC, Salah H, Popp T, Novikoff A, Breit A, Chubanov V, Müller TD, Zierler S, Gudermann T. Khajavi N, et al. Among authors: novikoff a. JCI Insight. 2023 Feb 8;8(3):e163397. doi: 10.1172/jci.insight.163397. JCI Insight. 2023. PMID: 36574297 Free PMC article.
Gut Peptide Agonism in the Treatment of Obesity and Diabetes.
Grandl G, Novikoff A, DiMarchi R, Tschöp MH, Müller TD. Grandl G, et al. Among authors: novikoff a. Compr Physiol. 2019 Dec 18;10(1):99-124. doi: 10.1002/cphy.c180044. Compr Physiol. 2019. PMID: 31853954 Review.
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity.
Jall S, De Angelis M, Lundsgaard AM, Fritzen AM, Nicolaisen TS, Klein AB, Novikoff A, Sachs S, Richter EA, Kiens B, Schramm KW, Tschöp MH, Stemmer K, Clemmensen C, Müller TD, Kleinert M. Jall S, et al. Among authors: novikoff a. Diabetologia. 2020 Jun;63(6):1236-1247. doi: 10.1007/s00125-020-05117-4. Epub 2020 Mar 6. Diabetologia. 2020. PMID: 32140744 Free PMC article.
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
Sekar R, Motzler K, Kwon Y, Novikoff A, Jülg J, Najafi B, Wang S, Warnke AL, Seitz S, Hass D, Gancheva S, Kahl S, Yang B, Finan B, Schwarz K, Okun JG, Roden M, Blüher M, Müller TD, Krahmer N, Behrends C, Plettenburg O, Miaczynska M, Herzig S, Zeigerer A. Sekar R, et al. Among authors: novikoff a. Cell Metab. 2022 Nov 1;34(11):1824-1842.e9. doi: 10.1016/j.cmet.2022.09.022. Epub 2022 Oct 14. Cell Metab. 2022. PMID: 36243006 Free article.
Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice.
Liskiewicz D, Zhang Q, Barthem CS, Jastroch M, Liskiewicz A, Khajavi N, Grandl G, Coupland C, Kleinert M, Garcia-Caceres C, Novikoff A, Maity G, Boehm U, Tschöp MH, Müller TD. Liskiewicz D, et al. Among authors: novikoff a. Mol Metab. 2023 Jun;72:101714. doi: 10.1016/j.molmet.2023.101714. Epub 2023 Mar 24. Mol Metab. 2023. PMID: 36966947 Free PMC article.
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
El K, Douros JD, Willard FS, Novikoff A, Sargsyan A, Perez-Tilve D, Wainscott DB, Yang B, Chen A, Wothe D, Coupland C, Tschöp MH, Finan B, D'Alessio DA, Sloop KW, Müller TD, Campbell JE. El K, et al. Among authors: novikoff a. Nat Metab. 2023 Jun;5(6):945-954. doi: 10.1038/s42255-023-00811-0. Epub 2023 Jun 5. Nat Metab. 2023. PMID: 37277609 Free PMC article.
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice.
Liskiewicz A, Khalil A, Liskiewicz D, Novikoff A, Grandl G, Maity-Kumar G, Gutgesell RM, Bakhti M, Bastidas-Ponce A, Czarnecki O, Makris K, Lickert H, Feuchtinger A, Tost M, Coupland C, Ständer L, Akindehin S, Prakash S, Abrar F, Castelino RL, He Y, Knerr PJ, Yang B, Hogendorf WFJ, Zhang S, Hofmann SM, Finan B, DiMarchi RD, Tschöp MH, Douros JD, Müller TD. Liskiewicz A, et al. Among authors: novikoff a. Nat Metab. 2023 Dec;5(12):2075-2085. doi: 10.1038/s42255-023-00931-7. Epub 2023 Nov 9. Nat Metab. 2023. PMID: 37946085 Free PMC article.
136 results