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Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.
La Regina G, Bai R, Rensen WM, Di Cesare E, Coluccia A, Piscitelli F, Famiglini V, Reggio A, Nalli M, Pelliccia S, Da Pozzo E, Costa B, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Santoni A, Li J, Miranda Cona M, Chen F, Ni Y, Brancale A, Dondio G, Vultaggio S, Varasi M, Mercurio C, Martini C, Hamel E, Lavia P, Novellino E, Silvestri R. La Regina G, et al. Among authors: novellino e. J Med Chem. 2013 Jan 10;56(1):123-49. doi: 10.1021/jm3013097. Epub 2012 Dec 27. J Med Chem. 2013. PMID: 23214452 Free PMC article.
Amino Acid derivatives as new zinc binding groups for the design of selective matrix metalloproteinase inhibitors.
Giustiniano M, Tortorella P, Agamennone M, Di Pizio A, Rossello A, Nuti E, Gomez-Monterrey I, Novellino E, Campiglia P, Vernieri E, Sala M, Bertamino A, Carotenuto A. Giustiniano M, et al. Among authors: novellino e. J Amino Acids. 2013;2013:178381. doi: 10.1155/2013/178381. Epub 2013 Mar 10. J Amino Acids. 2013. PMID: 23555050 Free PMC article.
A stereoselective approach to peptidomimetic BACE1 inhibitors.
Butini S, Gabellieri E, Brindisi M, Giovani S, Maramai S, Kshirsagar G, Guarino E, Brogi S, La Pietra V, Giustiniano M, Marinelli L, Novellino E, Campiani G, Cappelli A, Gemma S. Butini S, et al. Among authors: novellino e. Eur J Med Chem. 2013;70:233-47. doi: 10.1016/j.ejmech.2013.09.056. Epub 2013 Oct 6. Eur J Med Chem. 2013. PMID: 24158015
Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors.
La Pietra V, La Regina G, Coluccia A, Famiglini V, Pelliccia S, Plotkin B, Eldar-Finkelman H, Brancale A, Ballatore C, Crowe A, Brunden KR, Marinelli L, Novellino E, Silvestri R. La Pietra V, et al. Among authors: novellino e. J Med Chem. 2013 Dec 27;56(24):10066-78. doi: 10.1021/jm401466v. Epub 2013 Dec 11. J Med Chem. 2013. PMID: 24295046
739 results