Novellino E - Search Results

1

Spirohydantoin derivatives of thiopyrano[2,3-b]pyridin-4(4H)-one as potent in vitro and in vivo aldose reductase inhibitors.

Da Settimo F, Primofiore G, La Motta C, Salerno S, Novellino E, Greco G, Lavecchia A, Laneri S, Boldrini E. Da Settimo F, et al. Among authors: novellino e. Bioorg Med Chem. 2005 Jan 17;13(2):491-9. doi: 10.1016/j.bmc.2004.10.019. Bioorg Med Chem. 2005. PMID: 15598571

2

Design, synthesis and biological evaluation of novel N-alkyl- and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs) as novel A(1) adenosine receptor antagonists.

Novellino E, Abignente E, Cosimelli B, Greco G, Iadanza M, Laneri S, Lavecchia A, Rimoli MG, Settimo FD, Primofiore G, Tuscano D, Trincavelli L, Martini C. Novellino E, et al. J Med Chem. 2002 Nov 7;45(23):5030-6. doi: 10.1021/jm020911e. J Med Chem. 2002. PMID: 12408713

3

Novel, highly potent aldose reductase inhibitors: cyano(2-oxo-2,3-dihydroindol-3-yl)acetic acid derivatives.

Da Settimo F, Primofiore G, Da Settimo A, La Motta C, Simorini F, Novellino E, Greco G, Lavecchia A, Boldrini E. Da Settimo F, et al. Among authors: novellino e. J Med Chem. 2003 Apr 10;46(8):1419-28. doi: 10.1021/jm030762f. J Med Chem. 2003. PMID: 12672241

4

N,N-dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of potent and selective ligands at the peripheral benzodiazepine receptor.

Primofiore G, Da Settimo F, Taliani S, Simorini F, Patrizi MP, Novellino E, Greco G, Abignente E, Costa B, Chelli B, Martini C. Primofiore G, et al. Among authors: novellino e. J Med Chem. 2004 Mar 25;47(7):1852-5. doi: 10.1021/jm030973k. J Med Chem. 2004. PMID: 15027878 Free article.

5

High affinity central benzodiazepine receptor ligands: synthesis and biological evaluation of a series of phenyltriazolobenzotriazindione derivatives.

Primofiore G, Da Settimo F, Taliani S, Salerno S, Novellino E, Greco G, Cosimelli B, Besnard F, Costa B, Montali M, Martini C. Primofiore G, et al. Among authors: novellino e. J Med Chem. 2005 Apr 21;48(8):2936-43. doi: 10.1021/jm0408722. J Med Chem. 2005. PMID: 15828832

6

Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.

Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Da Settimo F, et al. Among authors: novellino e. J Med Chem. 2005 Aug 11;48(16):5162-74. doi: 10.1021/jm050136d. J Med Chem. 2005. PMID: 16078836

7

Naphtho[1,2-d]isothiazole acetic acid derivatives as a novel class of selective aldose reductase inhibitors.

Da Settimo F, Primofiore G, La Motta C, Sartini S, Taliani S, Simorini F, Marini AM, Lavecchia A, Novellino E, Boldrini E. Da Settimo F, et al. Among authors: novellino e. J Med Chem. 2005 Nov 3;48(22):6897-907. doi: 10.1021/jm050382p. J Med Chem. 2005. PMID: 16250648

8

Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides.

Primofiore G, Da Settimo F, Marini AM, Taliani S, La Motta C, Simorini F, Novellino E, Greco G, Cosimelli B, Ehlardo M, Sala A, Besnard F, Montali M, Martini C. Primofiore G, et al. Among authors: novellino e. J Med Chem. 2006 Apr 20;49(8):2489-95. doi: 10.1021/jm0511841. J Med Chem. 2006. PMID: 16610792

9

Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.

Primofiore G, Taliani S, Da Settimo F, Marini AM, La Motta C, Simorini F, Patrizi MP, Sergianni V, Novellino E, Greco G, Cosimelli B, Calderone V, Montali M, Besnard F, Martini C. Primofiore G, et al. Among authors: novellino e. J Med Chem. 2007 Apr 5;50(7):1627-34. doi: 10.1021/jm0607707. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335185

10

Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity.

La Motta C, Sartini S, Mugnaini L, Simorini F, Taliani S, Salerno S, Marini AM, Da Settimo F, Lavecchia A, Novellino E, Cantore M, Failli P, Ciuffi M. La Motta C, et al. Among authors: novellino e. J Med Chem. 2007 Oct 4;50(20):4917-27. doi: 10.1021/jm070398a. Epub 2007 Sep 11. J Med Chem. 2007. PMID: 17845019

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