Nosol K - Search Results

1

Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP.

Liu H, Zakrzewicz D, Nosol K, Irobalieva RN, Mukherjee S, Bang-Sørensen R, Goldmann N, Kunz S, Rossi L, Kossiakoff AA, Urban S, Glebe D, Geyer J, Locher KP. Liu H, et al. Among authors: nosol k. Nat Commun. 2024 Mar 20;15(1):2476. doi: 10.1038/s41467-024-46706-w. Nat Commun. 2024. PMID: 38509088 Free PMC article.

2

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.

Liu H, Irobalieva RN, Kowal J, Ni D, Nosol K, Bang-Sørensen R, Lancien L, Stahlberg H, Stieger B, Locher KP. Liu H, et al. Among authors: nosol k. Nat Commun. 2023 Nov 10;14(1):7296. doi: 10.1038/s41467-023-43109-1. Nat Commun. 2023. PMID: 37949847 Free PMC article.

3

Structure of human drug transporters OATP1B1 and OATP1B3.

Ciută AD, Nosol K, Kowal J, Mukherjee S, Ramírez AS, Stieger B, Kossiakoff AA, Locher KP. Ciută AD, et al. Among authors: nosol k. Nat Commun. 2023 Sep 18;14(1):5774. doi: 10.1038/s41467-023-41552-8. Nat Commun. 2023. PMID: 37723174 Free PMC article.

4

Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.

Leonhardt SA, Purdy MD, Grover JR, Yang Z, Poulos S, McIntire WE, Tatham EA, Erramilli SK, Nosol K, Lai KK, Ding S, Lu M, Uchil PD, Finzi A, Rein A, Kossiakoff AA, Mothes W, Yeager M. Leonhardt SA, et al. Among authors: nosol k. Nat Commun. 2023 Jul 20;14(1):4368. doi: 10.1038/s41467-023-39262-2. Nat Commun. 2023. PMID: 37474505 Free PMC article.

5

Production of Human ABC Transporters and Oligosaccharyltransferase Complexes for Structural Studies.

Ramírez AS, Nosol K, Locher KP. Ramírez AS, et al. Among authors: nosol k. Methods Mol Biol. 2022;2507:273-294. doi: 10.1007/978-1-0716-2368-8_14. Methods Mol Biol. 2022. PMID: 35773587

6

Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.

Liu H, Irobalieva RN, Bang-Sørensen R, Nosol K, Mukherjee S, Agrawal P, Stieger B, Kossiakoff AA, Locher KP. Liu H, et al. Among authors: nosol k. Cell Res. 2022 Aug;32(8):773-776. doi: 10.1038/s41422-022-00680-4. Epub 2022 Jun 20. Cell Res. 2022. PMID: 35726088 Free PMC article. No abstract available.

7

Structural basis of lipopolysaccharide maturation by the O-antigen ligase.

Ashraf KU, Nygaard R, Vickery ON, Erramilli SK, Herrera CM, McConville TH, Petrou VI, Giacometti SI, Dufrisne MB, Nosol K, Zinkle AP, Graham CLB, Loukeris M, Kloss B, Skorupinska-Tudek K, Swiezewska E, Roper DI, Clarke OB, Uhlemann AC, Kossiakoff AA, Trent MS, Stansfeld PJ, Mancia F. Ashraf KU, et al. Among authors: nosol k. Nature. 2022 Apr;604(7905):371-376. doi: 10.1038/s41586-022-04555-x. Epub 2022 Apr 6. Nature. 2022. PMID: 35388216 Free PMC article.

8

Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations.

Urgaonkar S, Nosol K, Said AM, Nasief NN, Bu Y, Locher KP, Lau JYN, Smolinski MP. Urgaonkar S, et al. Among authors: nosol k. J Med Chem. 2022 Jan 13;65(1):191-216. doi: 10.1021/acs.jmedchem.1c01272. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34928144

9

Structures of ABCB4 provide insight into phosphatidylcholine translocation.

Nosol K, Bang-Sørensen R, Irobalieva RN, Erramilli SK, Stieger B, Kossiakoff AA, Locher KP. Nosol K, et al. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2106702118. doi: 10.1073/pnas.2106702118. Proc Natl Acad Sci U S A. 2021. PMID: 34385322 Free PMC article.

10

Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.

Nosol K, Romane K, Irobalieva RN, Alam A, Kowal J, Fujita N, Locher KP. Nosol K, et al. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26245-26253. doi: 10.1073/pnas.2010264117. Epub 2020 Oct 5. Proc Natl Acad Sci U S A. 2020. PMID: 33020312 Free PMC article.

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