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High-throughput platforms for metabolomics.
de Raad M, Fischer CR, Northen TR. de Raad M, et al. Among authors: northen tr. Curr Opin Chem Biol. 2016 Feb;30:7-13. doi: 10.1016/j.cbpa.2015.10.012. Epub 2015 Nov 4. Curr Opin Chem Biol. 2016. PMID: 26544850 Review.
Enzyme promiscuity shapes adaptation to novel growth substrates.
Guzmán GI, Sandberg TE, LaCroix RA, Nyerges Á, Papp H, de Raad M, King ZA, Hefner Y, Northen TR, Notebaart RA, Pál C, Palsson BO, Papp B, Feist AM. Guzmán GI, et al. Among authors: northen tr. Mol Syst Biol. 2019 Apr 8;15(4):e8462. doi: 10.15252/msb.20188462. Mol Syst Biol. 2019. PMID: 30962359 Free PMC article.
Lessons from Two Design-Build-Test-Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning.
Opgenorth P, Costello Z, Okada T, Goyal G, Chen Y, Gin J, Benites V, de Raad M, Northen TR, Deng K, Deutsch S, Baidoo EEK, Petzold CJ, Hillson NJ, Garcia Martin H, Beller HR. Opgenorth P, et al. Among authors: northen tr. ACS Synth Biol. 2019 Jun 21;8(6):1337-1351. doi: 10.1021/acssynbio.9b00020. Epub 2019 May 24. ACS Synth Biol. 2019. PMID: 31072100 Free article.
CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria.
Wang G, Zhao Z, Ke J, Engel Y, Shi YM, Robinson D, Bingol K, Zhang Z, Bowen B, Louie K, Wang B, Evans R, Miyamoto Y, Cheng K, Kosina S, De Raad M, Silva L, Luhrs A, Lubbe A, Hoyt DW, Francavilla C, Otani H, Deutsch S, Washton NM, Rubin EM, Mouncey NJ, Visel A, Northen T, Cheng JF, Bode HB, Yoshikuni Y. Wang G, et al. Nat Microbiol. 2019 Dec;4(12):2498-2510. doi: 10.1038/s41564-019-0573-8. Epub 2019 Oct 14. Nat Microbiol. 2019. PMID: 31611640
185 results