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Page 1
Acid ceramidase inhibition: a novel target for cancer therapy.
Liu X, Elojeimy S, Turner LS, Mahdy AE, Zeidan YH, Bielawska A, Bielawski J, Dong JY, El-Zawahry AM, Guo GW, Hannun YA, Holman DH, Rubinchik S, Szulc Z, Keane TE, Tavassoli M, Norris JS. Liu X, et al. Among authors: norris js. Front Biosci. 2008 Jan 1;13:2293-8. doi: 10.2741/2843. Front Biosci. 2008. PMID: 17981711 Review.
Role of acid ceramidase in resistance to FasL: therapeutic approaches based on acid ceramidase inhibitors and FasL gene therapy.
Elojeimy S, Liu X, McKillop JC, El-Zawahry AM, Holman DH, Cheng JY, Meacham WD, Mahdy AE, Saad AF, Turner LS, Cheng J, A Day T, Dong JY, Bielawska A, Hannun YA, Norris JS. Elojeimy S, et al. Among authors: norris js. Mol Ther. 2007 Jul;15(7):1259-63. doi: 10.1038/sj.mt.6300167. Epub 2007 Apr 10. Mol Ther. 2007. PMID: 17426710 Free article.
New insights on the use of desipramine as an inhibitor for acid ceramidase.
Elojeimy S, Holman DH, Liu X, El-Zawahry A, Villani M, Cheng JC, Mahdy A, Zeidan Y, Bielwaska A, Hannun YA, Norris JS. Elojeimy S, et al. Among authors: norris js. FEBS Lett. 2006 Aug 21;580(19):4751-6. doi: 10.1016/j.febslet.2006.07.071. Epub 2006 Aug 4. FEBS Lett. 2006. PMID: 16901483 Free article.
Involvement of sphingolipids in apoptin-induced cell killing.
Liu X, Zeidan YH, Elojeimy S, Holman DH, El-Zawahry AM, Guo GW, Bielawska A, Bielawski J, Szulc Z, Rubinchik S, Dong JY, Keane TE, Tavassoli M, Hannun YA, Norris JS. Liu X, et al. Among authors: norris js. Mol Ther. 2006 Nov;14(5):627-36. doi: 10.1016/j.ymthe.2006.07.001. Epub 2006 Aug 22. Mol Ther. 2006. PMID: 16926120 Free article.
Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells.
Holman DH, Turner LS, El-Zawahry A, Elojeimy S, Liu X, Bielawski J, Szulc ZM, Norris K, Zeidan YH, Hannun YA, Bielawska A, Norris JS. Holman DH, et al. Among authors: norris k, norris js. Cancer Chemother Pharmacol. 2008 Feb;61(2):231-42. doi: 10.1007/s00280-007-0465-0. Epub 2007 Apr 12. Cancer Chemother Pharmacol. 2008. PMID: 17429631
Molecular targeting of acid ceramidase: implications to cancer therapy.
Zeidan YH, Jenkins RW, Korman JB, Liu X, Obeid LM, Norris JS, Hannun YA. Zeidan YH, et al. Among authors: norris js. Curr Drug Targets. 2008 Aug;9(8):653-61. doi: 10.2174/138945008785132358. Curr Drug Targets. 2008. PMID: 18691012 Free PMC article. Review.
Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer.
Mahdy AE, Cheng JC, Li J, Elojeimy S, Meacham WD, Turner LS, Bai A, Gault CR, McPherson AS, Garcia N, Beckham TH, Saad A, Bielawska A, Bielawski J, Hannun YA, Keane TE, Taha MI, Hammouda HM, Norris JS, Liu X. Mahdy AE, et al. Among authors: norris js. Mol Ther. 2009 Mar;17(3):430-8. doi: 10.1038/mt.2008.281. Epub 2008 Dec 23. Mol Ther. 2009. PMID: 19107118 Free PMC article.
154 results