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Combining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.
Mukherjee N, Almeida A, Partyka KA, Lu Y, Schwan JV, Lambert K, Rogers M, Robinson WA, Robinson SE, Applegate AJ, Amato CM, Luo Y, Fujita M, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: norris da. Oncotarget. 2016 Dec 20;7(51):84594-84607. doi: 10.18632/oncotarget.13141. Oncotarget. 2016. PMID: 27829238 Free PMC article.
BH3 mimetics induce apoptosis independent of DRP-1 in melanoma.
Mukherjee N, Strosnider A, Vagher B, Lambert KA, Slaven S, Robinson WA, Amato CM, Couts KL, Bemis JGT, Turner JA, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: norris da. Cell Death Dis. 2018 Sep 5;9(9):907. doi: 10.1038/s41419-018-0932-z. Cell Death Dis. 2018. PMID: 30185782 Free PMC article.
MCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells.
Mukherjee N, Skees J, Todd KJ, West DA, Lambert KA, Robinson WA, Amato CM, Couts KL, Van Gulick R, MacBeth M, Nassar K, Tan AC, Zhai Z, Fujita M, Bagby SM, Dart CR, Lambert JR, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: norris da. Cell Death Dis. 2020 Jun 8;11(6):443. doi: 10.1038/s41419-020-2646-2. Cell Death Dis. 2020. PMID: 32513939 Free PMC article.
Enrichment of Melanoma Stem-Like Cells via Sphere Assays.
Mukherjee N, Lambert KA, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: norris da. Methods Mol Biol. 2021;2265:185-199. doi: 10.1007/978-1-0716-1205-7_14. Methods Mol Biol. 2021. PMID: 33704715 Free PMC article.
Expression Differences in BCL2 Family Members between Uveal and Cutaneous Melanomas Account for Varying Sensitivity to BH3 Mimetics.
Mukherjee N, Dart CR, Amato CM, Honig-Frand A, Lambert JR, Lambert KA, Robinson WA, Tobin RP, McCarter MD, Couts KL, Fujita M, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: norris da. J Invest Dermatol. 2022 Jul;142(7):1912-1922.e7. doi: 10.1016/j.jid.2021.11.035. Epub 2021 Dec 20. J Invest Dermatol. 2022. PMID: 34942200 Free PMC article.
228 results