Nordlund P - Search Results

1

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

Martinez Molina D, Jafari R, Ignatushchenko M, Seki T, Larsson EA, Dan C, Sreekumar L, Cao Y, Nordlund P. Martinez Molina D, et al. Among authors: nordlund p. Science. 2013 Jul 5;341(6141):84-7. doi: 10.1126/science.1233606. Science. 2013. PMID: 23828940

2

The cellular thermal shift assay for evaluating drug target interactions in cells.

Jafari R, Almqvist H, Axelsson H, Ignatushchenko M, Lundbäck T, Nordlund P, Martinez Molina D. Jafari R, et al. Among authors: nordlund p. Nat Protoc. 2014 Sep;9(9):2100-22. doi: 10.1038/nprot.2014.138. Epub 2014 Aug 7. Nat Protoc. 2014. PMID: 25101824

3

Tracking cancer drugs in living cells by thermal profiling of the proteome.

Savitski MM, Reinhard FB, Franken H, Werner T, Savitski MF, Eberhard D, Martinez Molina D, Jafari R, Dovega RB, Klaeger S, Kuster B, Nordlund P, Bantscheff M, Drewes G. Savitski MM, et al. Among authors: nordlund p. Science. 2014 Oct 3;346(6205):1255784. doi: 10.1126/science.1255784. Epub 2014 Oct 2. Science. 2014. PMID: 25278616

4

The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies.

Martinez Molina D, Nordlund P. Martinez Molina D, et al. Among authors: nordlund p. Annu Rev Pharmacol Toxicol. 2016;56:141-61. doi: 10.1146/annurev-pharmtox-010715-103715. Epub 2015 Nov 9. Annu Rev Pharmacol Toxicol. 2016. PMID: 26566155 Review.

5

Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells.

Tan CSH, Go KD, Bisteau X, Dai L, Yong CH, Prabhu N, Ozturk MB, Lim YT, Sreekumar L, Lengqvist J, Tergaonkar V, Kaldis P, Sobota RM, Nordlund P. Tan CSH, et al. Among authors: nordlund p. Science. 2018 Mar 9;359(6380):1170-1177. doi: 10.1126/science.aan0346. Epub 2018 Feb 8. Science. 2018. PMID: 29439025

6

Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution.

Eshaghi S, Niegowski D, Kohl A, Martinez Molina D, Lesley SA, Nordlund P. Eshaghi S, et al. Among authors: nordlund p. Science. 2006 Jul 21;313(5785):354-7. doi: 10.1126/science.1127121. Science. 2006. PMID: 16857941

7

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil.

Almqvist H, Axelsson H, Jafari R, Dan C, Mateus A, Haraldsson M, Larsson A, Martinez Molina D, Artursson P, Lundbäck T, Nordlund P. Almqvist H, et al. Among authors: nordlund p. Nat Commun. 2016 Mar 24;7:11040. doi: 10.1038/ncomms11040. Nat Commun. 2016. PMID: 27010513 Free PMC article.

8

Catalysis within the lipid bilayer-structure and mechanism of the MAPEG family of integral membrane proteins.

Martinez Molina D, Eshaghi S, Nordlund P. Martinez Molina D, et al. Among authors: nordlund p. Curr Opin Struct Biol. 2008 Aug;18(4):442-9. doi: 10.1016/j.sbi.2008.04.005. Epub 2008 Jun 12. Curr Opin Struct Biol. 2008. PMID: 18550357

9

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions.

Lim YT, Prabhu N, Dai L, Go KD, Chen D, Sreekumar L, Egeblad L, Eriksson S, Chen L, Veerappan S, Teo HL, Tan CSH, Lengqvist J, Larsson A, Sobota RM, Nordlund P. Lim YT, et al. Among authors: nordlund p. PLoS One. 2018 Dec 6;13(12):e0208273. doi: 10.1371/journal.pone.0208273. eCollection 2018. PLoS One. 2018. PMID: 30521565 Free PMC article.

10

CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance.

Langebäck A, Bacanu S, Laursen H, Mout L, Seki T, Erkens-Schulze S, Ramos AD, Berggren A, Cao Y, Hartman J, van Weerden W, Bergh J, Nordlund P, Lööf S. Langebäck A, et al. Among authors: nordlund p. Sci Rep. 2019 Dec 18;9(1):19384. doi: 10.1038/s41598-019-55526-8. Sci Rep. 2019. PMID: 31852908 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

202 results

Search Page