Nonato MC - Search Results

1

Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.

Chibli LA, Schmidt TJ, Nonato MC, Calil FA, Da Costa FB. Chibli LA, et al. Among authors: nonato mc. Eur J Med Chem. 2018 Sep 5;157:852-866. doi: 10.1016/j.ejmech.2018.08.033. Epub 2018 Aug 16. Eur J Med Chem. 2018. PMID: 30145372

2

Cloning, expression, purification, and characterization of Leishmania major dihydroorotate dehydrogenase.

Feliciano PR, Cordeiro AT, Costa-Filho AJ, Nonato MC. Feliciano PR, et al. Among authors: nonato mc. Protein Expr Purif. 2006 Jul;48(1):98-103. doi: 10.1016/j.pep.2006.02.010. Epub 2006 Mar 10. Protein Expr Purif. 2006. PMID: 16600626

3

Crystallization and preliminary X-ray diffraction analysis of Leishmania major dihydroorotate dehydrogenase.

Cordeiro AT, Feliciano PR, Nonato MC. Cordeiro AT, et al. Among authors: nonato mc. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt 10):1049-51. doi: 10.1107/S1744309106038966. Epub 2006 Sep 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17012810 Free PMC article.

4

Defects in vesicle core induced by escherichia coli dihydroorotate dehydrogenase.

Couto SG, Nonato MC, Costa-Filho AJ. Couto SG, et al. Among authors: nonato mc. Biophys J. 2008 Mar 1;94(5):1746-53. doi: 10.1529/biophysj.107.120055. Epub 2007 Nov 9. Biophys J. 2008. PMID: 17993483 Free PMC article.

5

Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery.

Cheleski J, Rocha JR, Pinheiro MP, Wiggers HJ, da Silva AB, Nonato MC, Montanari CA. Cheleski J, et al. Among authors: nonato mc. Eur J Med Chem. 2010 Dec;45(12):5899-909. doi: 10.1016/j.ejmech.2010.09.055. Epub 2010 Oct 7. Eur J Med Chem. 2010. PMID: 20965617

6

Crystal structure of dihydroorotate dehydrogenase from Leishmania major.

Cordeiro AT, Feliciano PR, Pinheiro MP, Nonato MC. Cordeiro AT, et al. Among authors: nonato mc. Biochimie. 2012 Aug;94(8):1739-48. doi: 10.1016/j.biochi.2012.04.003. Epub 2012 Apr 21. Biochimie. 2012. PMID: 22542640 Free article.

7

Target sites for the design of anti-trypanosomatid drugs based on the structure of dihydroorotate dehydrogenase.

Pinheiro MP, Emery Fda S, Nonato MC. Pinheiro MP, et al. Among authors: nonato mc. Curr Pharm Des. 2013;19(14):2615-27. doi: 10.2174/1381612811319140011. Curr Pharm Des. 2013. PMID: 23116399 Review.

8

Recombinant production, crystallization and crystal structure determination of dihydroorotate dehydrogenase from Leishmania (Viannia) braziliensis.

Reis RA, Lorenzato E Jr, Silva VC, Nonato MC. Reis RA, et al. Among authors: nonato mc. Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):547-52. doi: 10.1107/S2053230X15000886. Epub 2015 Apr 21. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25945707 Free PMC article.

9

The mechanistic study of Leishmania major dihydro-orotate dehydrogenase based on steady- and pre-steady-state kinetic analysis.

Reis RA, Ferreira P, Medina M, Nonato MC. Reis RA, et al. Among authors: nonato mc. Biochem J. 2016 Mar 1;473(5):651-60. doi: 10.1042/BJ20150921. Epub 2015 Dec 11. Biochem J. 2016. PMID: 26656485

10

Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors.

Azeredo LFSP, Coutinho JP, Jabor VAP, Feliciano PR, Nonato MC, Kaiser CR, Menezes CMS, Hammes ASO, Caffarena ER, Hoelz LVB, de Souza NB, Pereira GAN, Cerávolo IP, Krettli AU, Boechat N. Azeredo LFSP, et al. Among authors: nonato mc. Eur J Med Chem. 2017 Jan 27;126:72-83. doi: 10.1016/j.ejmech.2016.09.073. Epub 2016 Sep 30. Eur J Med Chem. 2017. PMID: 27744189

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