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Methylglyoxal: a novel upstream regulator of DNA methylation.
Dube G, Tiamiou A, Bizet M, Boumahd Y, Gasmi I, Crake R, Bellier J, Nokin MJ, Calonne E, Deplus R, Wissocq T, Peulen O, Castronovo V, Fuks F, Bellahcène A. Dube G, et al. Among authors: nokin mj. J Exp Clin Cancer Res. 2023 Mar 31;42(1):78. doi: 10.1186/s13046-023-02637-w. J Exp Clin Cancer Res. 2023. PMID: 36998085 Free PMC article.
Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer.
Bellier J, Nokin MJ, Lardé E, Karoyan P, Peulen O, Castronovo V, Bellahcène A. Bellier J, et al. Among authors: nokin mj. Diabetes Res Clin Pract. 2019 Feb;148:200-211. doi: 10.1016/j.diabres.2019.01.002. Epub 2019 Jan 18. Diabetes Res Clin Pract. 2019. PMID: 30664892 Review.
Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.
Nokin MJ, Bellier J, Durieux F, Peulen O, Rademaker G, Gabriel M, Monseur C, Charloteaux B, Verbeke L, van Laere S, Roncarati P, Herfs M, Lambert C, Scheijen J, Schalkwijk C, Colige A, Caers J, Delvenne P, Turtoi A, Castronovo V, Bellahcène A. Nokin MJ, et al. Breast Cancer Res. 2019 Jan 23;21(1):11. doi: 10.1186/s13058-018-1095-7. Breast Cancer Res. 2019. PMID: 30674353 Free PMC article.
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A. Nokin MJ, et al. Elife. 2016 Oct 19;5:e19375. doi: 10.7554/eLife.19375. Elife. 2016. PMID: 27759563 Free PMC article.
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.
Chiavarina B, Nokin MJ, Bellier J, Durieux F, Bletard N, Sherer F, Lovinfosse P, Peulen O, Verset L, Dehon R, Demetter P, Turtoi A, Uchida K, Goldman S, Hustinx R, Delvenne P, Castronovo V, Bellahcène A. Chiavarina B, et al. Among authors: nokin mj. Int J Mol Sci. 2017 Jan 21;18(1):213. doi: 10.3390/ijms18010213. Int J Mol Sci. 2017. PMID: 28117708 Free PMC article.
Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab.
Bellier J, Nokin MJ, Caprasse M, Tiamiou A, Blomme A, Scheijen JL, Koopmansch B, MacKay GM, Chiavarina B, Costanza B, Rademaker G, Durieux F, Agirman F, Maloujahmoum N, Cusumano PG, Lovinfosse P, Leung HY, Lambert F, Bours V, Schalkwijk CG, Hustinx R, Peulen O, Castronovo V, Bellahcène A. Bellier J, et al. Among authors: nokin mj. Cell Rep. 2020 Feb 4;30(5):1400-1416.e6. doi: 10.1016/j.celrep.2020.01.012. Cell Rep. 2020. PMID: 32023458 Free article.
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