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The minipig in dermatotoxicology: methods and challenges.
Mahl JA, Vogel BE, Court M, Kolopp M, Roman D, Nogués V. Mahl JA, et al. Among authors: nogues v. Exp Toxicol Pathol. 2006 Jul;57(5-6):341-5. doi: 10.1016/j.etp.2006.03.004. Epub 2006 May 19. Exp Toxicol Pathol. 2006. PMID: 16713702
The utility of the minipig as an animal model in regulatory toxicology.
Bode G, Clausing P, Gervais F, Loegsted J, Luft J, Nogues V, Sims J; Steering Group of the RETHINK Project. Bode G, et al. Among authors: nogues v. J Pharmacol Toxicol Methods. 2010 Nov-Dec;62(3):196-220. doi: 10.1016/j.vascn.2010.05.009. Epub 2010 May 31. J Pharmacol Toxicol Methods. 2010. PMID: 20685310 Review.
A European pharmaceutical company initiative challenging the regulatory requirement for acute toxicity studies in pharmaceutical drug development.
Robinson S, Delongeas JL, Donald E, Dreher D, Festag M, Kervyn S, Lampo A, Nahas K, Nogues V, Ockert D, Quinn K, Old S, Pickersgill N, Somers K, Stark C, Stei P, Waterson L, Chapman K. Robinson S, et al. Among authors: nogues v. Regul Toxicol Pharmacol. 2008 Apr;50(3):345-52. doi: 10.1016/j.yrtph.2007.11.009. Epub 2007 Dec 5. Regul Toxicol Pharmacol. 2008. PMID: 18295384
A global pharmaceutical company initiative: an evidence-based approach to define the upper limit of body weight loss in short term toxicity studies.
Chapman K, Sewell F, Allais L, Delongeas JL, Donald E, Festag M, Kervyn S, Ockert D, Nogues V, Palmer H, Popovic M, Roosen W, Schoenmakers A, Somers K, Stark C, Stei P, Robinson S. Chapman K, et al. Among authors: nogues v. Regul Toxicol Pharmacol. 2013 Oct;67(1):27-38. doi: 10.1016/j.yrtph.2013.04.003. Epub 2013 Apr 19. Regul Toxicol Pharmacol. 2013. PMID: 23602904 Free article.
Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Prats-Ejarque G, Blanco JA, Salazar VA, Nogués VM, Moussaoui M, Boix E. Prats-Ejarque G, et al. Among authors: nogues vm. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):105-117. doi: 10.1016/j.bbagen.2018.09.021. Epub 2018 Oct 1. Biochim Biophys Acta Gen Subj. 2019. PMID: 30287244
17 results