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Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
Matesanz R, Trigili C, Rodríguez-Salarichs J, Zanardi I, Pera B, Nogales A, Fang WS, Jímenez-Barbero J, Canales A, Barasoain I, Ojima I, Díaz JF. Matesanz R, et al. Among authors: nogales a. Bioorg Med Chem. 2014 Sep 15;22(18):5078-90. doi: 10.1016/j.bmc.2014.05.048. Epub 2014 Jun 19. Bioorg Med Chem. 2014. PMID: 25047938 Free article.
Modulation of microtubule interprotofilament interactions by modified taxanes.
Matesanz R, Rodríguez-Salarichs J, Pera B, Canales A, Andreu JM, Jiménez-Barbero J, Bras W, Nogales A, Fang WS, Díaz JF. Matesanz R, et al. Among authors: nogales a. Biophys J. 2011 Dec 21;101(12):2970-80. doi: 10.1016/j.bpj.2011.11.005. Epub 2011 Dec 20. Biophys J. 2011. PMID: 22208196 Free PMC article.
Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.
Trigili C, Barasoain I, Sánchez-Murcia PA, Bargsten K, Redondo-Horcajo M, Nogales A, Gardner NM, Meyer A, Naylor GJ, Gómez-Rubio E, Gago F, Steinmetz MO, Paterson I, Prota AE, Díaz JF. Trigili C, et al. Among authors: nogales a. ACS Omega. 2016 Dec 31;1(6):1192-1204. doi: 10.1021/acsomega.6b00317. Epub 2016 Dec 13. ACS Omega. 2016. PMID: 30023505 Free PMC article.
Cooperativity of the beta-relaxations in aromatic polymers.
Sanz A, Nogales A, Ezquerra TA, Lotti N, Finelli L. Sanz A, et al. Among authors: nogales a. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Aug;70(2 Pt 1):021502. doi: 10.1103/PhysRevE.70.021502. Epub 2004 Aug 10. Phys Rev E Stat Nonlin Soft Matter Phys. 2004. PMID: 15447491
Stacking of main chain-crown ether polymers in thin films.
Rueda DR, Nogales A, Hernandez JJ, García-Gutiérrez MC, Ezquerra TA, Roth SV, Zolotukhin MG, Serna R. Rueda DR, et al. Among authors: nogales a. Langmuir. 2007 Dec 4;23(25):12677-81. doi: 10.1021/la701734y. Epub 2007 Oct 31. Langmuir. 2007. PMID: 17973406
197 results