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De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor.
Cell Mol Life Sci. 2024 Mar 28;81(1):153. doi: 10.1007/s00018-023-05069-z.
Cell Mol Life Sci. 2024.
PMID: 38538865
Free PMC article.
Role of UDP-Glycosyltransferase (ugt) Genes in Detoxification and Glycosylation of 1-Hydroxyphenazine (1-HP) in Caenorhabditis elegans.
Asif MZ, Nocilla KA, Ngo L, Shah M, Smadi Y, Hafeez Z, Parnes M, Manson A, Glushka JN, Leach FE 3rd, Edison AS.
Asif MZ, et al. Among authors: nocilla ka.
Chem Res Toxicol. 2024 Apr 15;37(4):590-599. doi: 10.1021/acs.chemrestox.3c00410. Epub 2024 Mar 15.
Chem Res Toxicol. 2024.
PMID: 38488606
Free PMC article.
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Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor.
D'Erasmo MP, Akins NS, Ma P, Jing Y, Swanger SA, Sharma SK, Bartsch PW, Menaldino DS, Arcoria PJ, Bui TT, Pons-Bennaceur A, Le P, Allen JP, Ullman EZ, Nocilla KA, Zhang J, Perszyk RE, Kim S, Acker TM, Taz A, Burton SL, Coe K, Fritzemeier RG, Burnashev N, Yuan H, Liotta DC, Traynelis SF.
D'Erasmo MP, et al. Among authors: nocilla ka.
ACS Chem Neurosci. 2023 Sep 6;14(17):3059-3076. doi: 10.1021/acschemneuro.3c00181. Epub 2023 Aug 11.
ACS Chem Neurosci. 2023.
PMID: 37566734
Free PMC article.
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Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function.
Myers SJ, Yuan H, Perszyk RE, Zhang J, Kim S, Nocilla KA, Allen JP, Bain JM, Lemke JR, Lal D, Benke TA, Traynelis SF.
Myers SJ, et al. Among authors: nocilla ka.
Hum Mol Genet. 2023 Sep 16;32(19):2857-2871. doi: 10.1093/hmg/ddad104.
Hum Mol Genet. 2023.
PMID: 37369021
Free PMC article.
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Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening.
Xie L, McDaniel MJ, Perszyk RE, Kim S, Cappuccio G, Shapiro KA, Muñoz-Cabello B, Sanchez-Lara PA, Grand K, Zhang J, Nocilla KA, Sheikh R, Armengol L, Romano R, Pierson TM, Yuan H, Myers SJ, Traynelis SF.
Xie L, et al. Among authors: nocilla ka.
Cell Mol Life Sci. 2023 Mar 31;80(4):110. doi: 10.1007/s00018-023-04705-y.
Cell Mol Life Sci. 2023.
PMID: 37000222
Free PMC article.
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Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model.
Harris LD, Regan MC, Myers SJ, Nocilla KA, Akins NS, Tahirovic YA, Wilson LJ, Dingledine R, Furukawa H, Traynelis SF, Liotta DC.
Harris LD, et al. Among authors: nocilla ka.
ACS Chem Neurosci. 2023 Mar 1;14(5):917-935. doi: 10.1021/acschemneuro.2c00779. Epub 2023 Feb 13.
ACS Chem Neurosci. 2023.
PMID: 36779874
Free PMC article.
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A Plate Based Assay for Determination of the Median Lethal Dose of 1-Hydroxyphenazine in Caenorhabditis elegans.
Asif MZ, Van der Gaag VL, Guo J, Nocilla KA, Muzio CJ, Edison AS.
Asif MZ, et al. Among authors: nocilla ka.
MicroPubl Biol. 2021 Jan 13;2021:10.17912/micropub.biology.000352. doi: 10.17912/micropub.biology.000352.
MicroPubl Biol. 2021.
PMID: 33458604
Free PMC article.
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