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803 results

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Tackling gaps in developing life-changing treatments for dementia.
Mauricio R, Benn C, Davis J, Dawson G, Dawson LA, Evans A, Fox N, Gallacher J, Hutton M, Isaac J, Jones DNC, Jones L, Lalli G, Libri V, Lovestone S, Moody C, Noble W, Perry H, Pickett J, Reynolds D, Ritchie C, Rohrer JD, Routledge C, Rowe J, Snyder H, Spires-Jones T, Swartz J, Truyen L, Whiting P; Therapeutics for Dementia Consortium. Mauricio R, et al. Among authors: noble w. Alzheimers Dement (N Y). 2019 Jun 24;5:241-253. doi: 10.1016/j.trci.2019.05.001. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31297438 Free PMC article. Review.
Sleep well to slow Alzheimer's progression?
Noble W, Spires-Jones TL. Noble W, et al. Science. 2019 Feb 22;363(6429):813-814. doi: 10.1126/science.aaw5583. Science. 2019. PMID: 30792288 No abstract available.
Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial.
Howard R, Zubko O, Bradley R, Harper E, Pank L, O'Brien J, Fox C, Tabet N, Livingston G, Bentham P, McShane R, Burns A, Ritchie C, Reeves S, Lovestone S, Ballard C, Noble W, Nilforooshan R, Wilcock G, Gray R; Minocycline in Alzheimer Disease Efficacy (MADE) Trialist Group. Howard R, et al. Among authors: noble w. JAMA Neurol. 2020 Feb 1;77(2):164-174. doi: 10.1001/jamaneurol.2019.3762. JAMA Neurol. 2020. PMID: 31738372 Free PMC article. Clinical Trial.
Artificial intelligence for neurodegenerative experimental models.
Marzi SJ, Schilder BM, Nott A, Frigerio CS, Willaime-Morawek S, Bucholc M, Hanger DP, James C, Lewis PA, Lourida I, Noble W, Rodriguez-Algarra F, Sharif JA, Tsalenchuk M, Winchester LM, Yaman Ü, Yao Z; Deep Dementia Phenotyping (DEMON) Network; Ranson JM, Llewellyn DJ. Marzi SJ, et al. Among authors: noble w. Alzheimers Dement. 2023 Dec;19(12):5970-5987. doi: 10.1002/alz.13479. Epub 2023 Sep 28. Alzheimers Dement. 2023. PMID: 37768001 Review.
Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer's disease.
Rupawala H, Shah K, Davies C, Rose J, Colom-Cadena M, Peng X, Granat L, Aljuhani M, Mizuno K, Troakes C, Perez-Nievas BG, Morgan A, So PW, Hortobagyi T, Spires-Jones TL, Noble W, Giese KP. Rupawala H, et al. Among authors: noble w. Brain Commun. 2022 Jul 23;4(4):fcac192. doi: 10.1093/braincomms/fcac192. eCollection 2022. Brain Commun. 2022. PMID: 35928052 Free PMC article.
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.
Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S, Lin K, Breen G, Wroe R, To AW, Leroy K, Causevic M, Usardi A, Robinson M, Noble W, Williamson R, Lunnon K, Kellie S, Reynolds CH, Bazenet C, Hodges A, Brion JP, Stephenson J, Simons JP, Lovestone S. Killick R, et al. Among authors: noble w. Mol Psychiatry. 2014 Jan;19(1):88-98. doi: 10.1038/mp.2012.163. Epub 2012 Nov 20. Mol Psychiatry. 2014. PMID: 23164821 Free PMC article.
Trimming away tau in neurodegeneration.
Noble W, Hanger DP. Noble W, et al. Science. 2023 Jul 28;381(6656):377-378. doi: 10.1126/science.adj0256. Epub 2023 Jul 27. Science. 2023. PMID: 37499007
803 results