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Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets.
Fu C, Zhang X, Veri AO, Iyer KR, Lash E, Xue A, Yan H, Revie NM, Wong C, Lin ZY, Polvi EJ, Liston SD, VanderSluis B, Hou J, Yashiroda Y, Gingras AC, Boone C, O'Meara TR, O'Meara MJ, Noble S, Robbins N, Myers CL, Cowen LE. Fu C, et al. Among authors: noble s. Nat Commun. 2021 Nov 11;12(1):6497. doi: 10.1038/s41467-021-26850-3. Nat Commun. 2021. PMID: 34764269 Free PMC article.
A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans.
Brimacombe CA, Burke JE, Parsa JY, Catania S, O'Meara TR, Witchley JN, Burrack LS, Madhani HD, Noble SM. Brimacombe CA, et al. Among authors: noble sm. PLoS Biol. 2019 Jun 21;17(6):e3000331. doi: 10.1371/journal.pbio.3000331. eCollection 2019 Jun. PLoS Biol. 2019. PMID: 31226107 Free PMC article.
Adaptive immunity induces mutualism between commensal eukaryotes.
Ost KS, O'Meara TR, Stephens WZ, Chiaro T, Zhou H, Penman J, Bell R, Catanzaro JR, Song D, Singh S, Call DH, Hwang-Wong E, Hanson KE, Valentine JF, Christensen KA, O'Connell RM, Cormack B, Ibrahim AS, Palm NW, Noble SM, Round JL. Ost KS, et al. Among authors: noble sm. Nature. 2021 Aug;596(7870):114-118. doi: 10.1038/s41586-021-03722-w. Epub 2021 Jul 14. Nature. 2021. PMID: 34262174 Free PMC article.
887 results