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Cisplatin effect on digital cytomorphometric and bioinformatic tumor cell characteristics in rat ovarian cancer model-a preliminary study.
Zhilinskaya NT, Bespalov VG, Semenov AL, Ermakova ED, Tochilnikov GV, Barakova NV, Alexandrov VA, Baranenko DA. Zhilinskaya NT, et al. Pharmacol Rep. 2021 Apr;73(2):642-649. doi: 10.1007/s43440-020-00199-8. Epub 2021 Feb 19. Pharmacol Rep. 2021. PMID: 33604796
CONCLUSIONS: Data obtained suggest that cisplatin reduces the total cell number, the nuclear/cytoplasmic ratio and R-value thus indicates a decrease in cellular resistance and adaptive potential. ...
CONCLUSIONS: Data obtained suggest that cisplatin reduces the total cell number, the nuclear/cytoplasmic ratio and R-value thu …