Noël F - Search Results

1

Biosynthesis of human diazepam and clonazepam metabolites.

de Paula NC, Araujo Cordeiro KC, de Melo Souza PL, Nogueira DF, da Silva e Sousa DB, Costa MB, Noël F, de Oliveira V. de Paula NC, et al. Among authors: noel f. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1026-9. doi: 10.1016/j.bmcl.2015.01.025. Epub 2015 Jan 20. Bioorg Med Chem Lett. 2015. PMID: 25655722

2

Synthesis and preliminary pharmacological evaluation of new (+/-) 1,4-naphthoquinones structurally related to lapachol.

da Silva AJ, Buarque CD, Brito FV, Aurelian L, Macedo LF, Malkas LH, Hickey RJ, Lopes DV, Noël F, Murakami YL, Silva NM, Melo PA, Caruso RR, Castro NG, Costa PR. da Silva AJ, et al. Among authors: noel f. Bioorg Med Chem. 2002 Aug;10(8):2731-8. doi: 10.1016/s0968-0896(02)00100-1. Bioorg Med Chem. 2002. PMID: 12057662

3

Insights into the mechanism of Na+,K+-ATPase inhibition by 2-methoxy-3,8,9-trihydroxy coumestan.

Pôças ES, Touza NA, Pimenta PH, Leitão FB, Neto CD, da Silva AJ, Costa PR, Noël F. Pôças ES, et al. Among authors: noel f. Bioorg Med Chem. 2008 Oct 1;16(19):8801-5. doi: 10.1016/j.bmc.2008.09.007. Epub 2008 Sep 7. Bioorg Med Chem. 2008. PMID: 18805699

4

Design of new dopamine D2 receptor ligands: biosynthesis and pharmacological evaluation of the hydroxylated metabolite of LASSBio-581.

Pazini F, Menegatti R, Sabino JR, Andrade CH, Neves G, Rates SM, Noël F, Fraga CA, Barreiro EJ, de Oliveira V. Pazini F, et al. Among authors: noel f. Bioorg Med Chem Lett. 2010 May 1;20(9):2888-91. doi: 10.1016/j.bmcl.2010.03.034. Epub 2010 Mar 10. Bioorg Med Chem Lett. 2010. PMID: 20363131

5

Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound.

Gomes TF, Pompeu TE, Rodrigues DA, Noël F, Menegatti R, Andrade CH, Sabino JR, Gil ES, Dalla Costa T, Betti AH, Antonio CB, Rates SM, Fraga CA, Barreiro EJ, de Oliveira V. Gomes TF, et al. Among authors: noel f. Eur J Med Chem. 2013 Apr;62:214-21. doi: 10.1016/j.ejmech.2012.08.011. Epub 2012 Aug 20. Eur J Med Chem. 2013. PMID: 23353740

6

Anxiolytic- and antidepressant-like effects of new phenylpiperazine derivative LQFM005 and its hydroxylated metabolite in mice.

Moreira LKDS, Silva RR, da Silva DM, Mendes MAS, de Brito AF, de Carvalho FS, Sanz G, Rodrigues MF, da Silva ACG, Thomaz DV, de Oliveira V, Vaz BG, Lião LM, Valadares MC, Gil ES, Costa EA, Noël F, Menegatti R. Moreira LKDS, et al. Among authors: noel f. Behav Brain Res. 2022 Jan 24;417:113582. doi: 10.1016/j.bbr.2021.113582. Epub 2021 Sep 15. Behav Brain Res. 2022. PMID: 34536431

7

Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation.

da Silva AJM, Melo PA, Silva NM, Brito FV, Buarque CD, de Souza DV, Rodrigues VP, Poças ES, Noël F, Albuquerque EX, Costa PR. da Silva AJM, et al. Among authors: noel f. Bioorg Med Chem Lett. 2001 Feb 12;11(3):283-6. doi: 10.1016/s0960-894x(00)00621-1. Bioorg Med Chem Lett. 2001. PMID: 11212092

8

Stereoselective synthesis and preliminary evaluation of new D-3-heteroarylcarbonylalanines as ligands of the NMDA receptor.

Lima PG, Caruso RR, Alves SO, Pessôa RF, Mendonça-Silva DL, Nunes RJ, Noël F, Castro NG, Costa PR. Lima PG, et al. Among authors: noel f. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4399-403. doi: 10.1016/j.bmcl.2004.06.062. Bioorg Med Chem Lett. 2004. PMID: 15357961

9

Structure-activity relationship of wedelolactone analogues: structural requirements for inhibition of Na+, K+ -ATPase and binding to the central benzodiazepine receptor.

Pôças ES, Lopes DV, da Silva AJ, Pimenta PH, Leitão FB, Netto CD, Buarque CD, Brito FV, Costa PR, Noël F. Pôças ES, et al. Among authors: noel f. Bioorg Med Chem. 2006 Dec 1;14(23):7962-6. doi: 10.1016/j.bmc.2006.07.053. Epub 2006 Aug 30. Bioorg Med Chem. 2006. PMID: 16945543

10

Pharmacokinetic/pharmacodynamic modeling of psychomotor impairment induced by oral clonazepam in healthy volunteers.

dos Santos FM, Gonçalves JC, Caminha R, da Silveira GE, Neves CS, Gram KR, Ferreira CT, Jacqmin P, Noël F. dos Santos FM, et al. Among authors: noel f. Ther Drug Monit. 2009 Oct;31(5):566-74. doi: 10.1097/FTD.0b013e3181b1dd76. Ther Drug Monit. 2009. PMID: 19730280 Clinical Trial.

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