Nnane IP - Search Results

1

Modification of the Fc Region of a Human Anti-oncostatin M Monoclonal Antibody for Higher Affinity to FcRn Receptor and Extension of Half-life in Cynomolgus Monkeys.

Nnane IP, Han C, Jiao Q, Tam SH, Davis HM, Xu Z. Nnane IP, et al. Basic Clin Pharmacol Toxicol. 2017 Jul;121(1):13-21. doi: 10.1111/bcpt.12761. Epub 2017 Mar 8. Basic Clin Pharmacol Toxicol. 2017. PMID: 28132416 Free article.

2

Safety, tolerability and pharmacokinetics of a human anti-interleukin-13 monoclonal antibody (CNTO 5825) in an ascending single-dose first-in-human study.

van Hartingsveldt B, Nnane IP, Bouman-Thio E, Loza MJ, Piantone A, Davis HM, Petty KJ. van Hartingsveldt B, et al. Among authors: nnane ip. Br J Clin Pharmacol. 2013 May;75(5):1289-98. doi: 10.1111/j.1365-2125.2012.04477.x. Br J Clin Pharmacol. 2013. PMID: 23043368 Free PMC article. Clinical Trial.

3

Non-Clinical Pharmacokinetics, Prediction of Human Pharmacokinetics and First-in-Human Dose Selection for CNTO 5825, an Anti-Interleukin-13 Monoclonal Antibody.

Nnane IP, Xu Z, Zhou H, Davis HM. Nnane IP, et al. Basic Clin Pharmacol Toxicol. 2015 Oct;117(4):219-25. doi: 10.1111/bcpt.12391. Epub 2015 Mar 5. Basic Clin Pharmacol Toxicol. 2015. PMID: 25683750 Free article.

4

The first-in-human study of CNTO 7160, an anti-interleukin-33 receptor monoclonal antibody, in healthy subjects and patients with asthma or atopic dermatitis.

Nnane I, Frederick B, Yao Z, Raible D, Shu C, Badorrek P, van den Boer M, Branigan P, Duffy K, Baribaud F, Fink D, Yang TY, Xu Z. Nnane I, et al. Br J Clin Pharmacol. 2020 Dec;86(12):2507-2518. doi: 10.1111/bcp.14361. Epub 2020 Jun 14. Br J Clin Pharmacol. 2020. PMID: 32415720 Free PMC article. Clinical Trial.

5

Pharmacokinetics, Pharmacodynamics, Immunogenicity, Safety, and Tolerability of JNJ-61178104, a Novel Tumor Necrosis Factor-Alpha and Interleukin-17A Bispecific Antibody, in Healthy Subjects.

Akpalu DE, Frederick B, Nnane IP, Yao Z, Shen F, Ort T, Fink D, Dogmanits S, Raible D, Sharma A, Xu Z. Akpalu DE, et al. Among authors: nnane ip. J Clin Pharmacol. 2019 Jul;59(7):968-978. doi: 10.1002/jcph.1393. Epub 2019 Feb 18. J Clin Pharmacol. 2019. PMID: 30776134 Clinical Trial.

6

Unexpected Toxicology Findings in Rats Dosed With an Antihuman IL-13 Monoclonal Antibody.

Martin PL, Nnane IP, Branigan P, Louden C. Martin PL, et al. Among authors: nnane ip. Int J Toxicol. 2015 Sep-Oct;34(5):393-407. doi: 10.1177/1091581815591840. Epub 2015 Jun 29. Int J Toxicol. 2015. PMID: 26124191

7

Population Pharmacokinetics and Exposure-Response Modeling of Daratumumab Subcutaneous Administration in Patients With Light-Chain Amyloidosis.

Luo MM, Zhu PP, Nnane I, Xiong Y, Merlini G, Comenzo RL, Kastritis E, Wechalekar AD, Weiss BM, Tran N, Qin X, Vermeulen J, Sharma A, Sun YN, Zhou H. Luo MM, et al. J Clin Pharmacol. 2022 May;62(5):656-669. doi: 10.1002/jcph.1994. Epub 2021 Nov 28. J Clin Pharmacol. 2022. PMID: 34708423

8

Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A.

Zheng S, Shen F, Jones B, Fink D, Geist B, Nnane I, Zhou Z, Hall J, Malaviya R, Ort T, Wang W. Zheng S, et al. MAbs. 2020 Jan-Dec;12(1):1770018. doi: 10.1080/19420862.2020.1770018. MAbs. 2020. PMID: 32544369 Free PMC article.

9

Pharmacokinetics and Safety of Single Intravenous Doses of JNJ-54452840, an Anti-β1-Adrenergic Receptor Antibody Cyclopeptide, in Healthy Male Japanese and Caucasian Participants.

Nnane IP, Plotnikov AH, Peters G, Johnson M, Kojak C, Vutikullird A, Ariyawansa J, De Vries R, Davies BE. Nnane IP, et al. Clin Pharmacokinet. 2016 Feb;55(2):225-36. doi: 10.1007/s40262-015-0309-8. Clin Pharmacokinet. 2016. PMID: 26242382 Clinical Trial.

10

Split First Dose Administration of Intravenous Daratumumab for the Treatment of Multiple Myeloma (MM): Clinical and Population Pharmacokinetic Analyses.

Xu XS, Moreau P, Usmani SZ, Lonial S, Jakubowiak A, Oriol A, Krishnan A, Bladé J, Luo M, Sun YN, Zhou H, Nnane I, Deraedt W, Qi M, Ukropec J, Clemens PL. Xu XS, et al. Adv Ther. 2020 Apr;37(4):1464-1478. doi: 10.1007/s12325-020-01247-8. Epub 2020 Feb 20. Adv Ther. 2020. PMID: 32078124 Free PMC article. Clinical Trial.

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