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Integration of High-Throughput Imaging and Multiparametric Metabolic Profiling Reveals a Mitochondrial Mechanism of Tenofovir Toxicity.
Pearson A, Haenni D, Bouitbir J, Hunt M, Payne BAI, Sachdeva A, Hung RKY, Post FA, Connolly J, Nlandu-Khodo S, Jankovic N, Bugarski M, Hall AM. Pearson A, et al. Among authors: nlandu khodo s. Function (Oxf). 2022 Dec 24;4(1):zqac065. doi: 10.1093/function/zqac065. eCollection 2023. Function (Oxf). 2022. PMID: 36654930 Free PMC article.
Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease.
Nlandu-Khodo S, Osaki Y, Scarfe L, Yang H, Phillips-Mignemi M, Tonello J, Saito-Diaz K, Neelisetty S, Ivanova A, Huffstater T, McMahon R, Taketo MM, deCaestecker M, Kasinath B, Harris RC, Lee E, Gewin LS. Nlandu-Khodo S, et al. JCI Insight. 2020 May 21;5(10):e135454. doi: 10.1172/jci.insight.135454. JCI Insight. 2020. PMID: 32369448 Free PMC article.
Novel kidney dissociation protocol and image-based flow cytometry facilitate improved analysis of injured proximal tubules.
Manolopoulou M, Matlock BK, Nlandu-Khodo S, Simmons AJ, Lau KS, Phillips-Mignemi M, Ivanova A, Alford CE, Flaherty DK, Gewin LS. Manolopoulou M, et al. Among authors: nlandu khodo s. Am J Physiol Renal Physiol. 2019 May 1;316(5):F847-F855. doi: 10.1152/ajprenal.00354.2018. Epub 2019 Feb 13. Am J Physiol Renal Physiol. 2019. PMID: 30759021 Free PMC article.
Blocking TGF-β and β-Catenin Epithelial Crosstalk Exacerbates CKD.
Nlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LS. Nlandu-Khodo S, et al. J Am Soc Nephrol. 2017 Dec;28(12):3490-3503. doi: 10.1681/ASN.2016121351. Epub 2017 Jul 12. J Am Soc Nephrol. 2017. PMID: 28701516 Free PMC article.
Deleting the TGF-β receptor in proximal tubules impairs HGF signaling.
Nlandu Khodo S, Neelisetty S, Woodbury L, Green E, Harris RC, Zent R, Gewin L. Nlandu Khodo S, et al. Am J Physiol Renal Physiol. 2016 Mar 15;310(6):F499-510. doi: 10.1152/ajprenal.00446.2015. Epub 2016 Jan 6. Am J Physiol Renal Physiol. 2016. PMID: 26739889 Free PMC article.