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Small Molecule Modulation of Proteasome Assembly.
Njomen E, Osmulski PA, Jones CL, Gaczynska M, Tepe JJ. Njomen E, et al. Biochemistry. 2018 Jul 17;57(28):4214-4224. doi: 10.1021/acs.biochem.8b00579. Epub 2018 Jun 27. Biochemistry. 2018. PMID: 29897236 Free PMC article.
Regulation of Autophagic Flux by the 20S Proteasome.
Njomen E, Tepe JJ. Njomen E, et al. Cell Chem Biol. 2019 Sep 19;26(9):1283-1294.e5. doi: 10.1016/j.chembiol.2019.07.002. Epub 2019 Jul 18. Cell Chem Biol. 2019. PMID: 31327703 Free PMC article.
Small Molecule 20S Proteasome Enhancer Regulates MYC Protein Stability and Exhibits Antitumor Activity in Multiple Myeloma.
Njomen E, Vanecek A, Lansdell TA, Yang YT, Schall PZ, Harris CM, Bernard MP, Isaac D, Alkharabsheh O, Al-Janadi A, Giletto MB, Ellsworth E, Taylor C, Tang T, Lau S, Bailie M, Bernard JJ, Yuzbasiyan-Gurkan V, Tepe JJ. Njomen E, et al. Biomedicines. 2022 Apr 19;10(5):938. doi: 10.3390/biomedicines10050938. Biomedicines. 2022. PMID: 35625675 Free PMC article.
Redirecting the pioneering function of FOXA1 with covalent small molecules.
Won SJ, Zhang Y, Reinhardt CJ, MacRae NS, DeMeester KE, Njomen E, Hargis LM, Remsberg JR, Melillo B, Cravatt BF, Erb MA. Won SJ, et al. Among authors: njomen e. bioRxiv [Preprint]. 2024 Mar 21:2024.03.21.586158. doi: 10.1101/2024.03.21.586158. bioRxiv. 2024. PMID: 38562719 Free PMC article. Preprint.
15 results