Nixon M - Search Results

1

Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.

Bell RMB, Villalobos E, Nixon M, Miguelez-Crespo A, Murphy L, Fawkes A, Coutts A, Sharp MGF, Koerner MV, Allan E, Meijer OC, Houtman R, Odermatt A, Beck KR, Denham SG, Lee P, Homer NZM, Walker BR, Morgan RA. Bell RMB, et al. Among authors: nixon m. Mol Metab. 2021 Jun;48:101225. doi: 10.1016/j.molmet.2021.101225. Epub 2021 Mar 27. Mol Metab. 2021. PMID: 33785425 Free PMC article.

2

5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects.

Yang C, Nixon M, Kenyon CJ, Livingstone DE, Duffin R, Rossi AG, Walker BR, Andrew R. Yang C, et al. Among authors: nixon m. Br J Pharmacol. 2011 Nov;164(6):1661-71. doi: 10.1111/j.1476-5381.2011.01465.x. Br J Pharmacol. 2011. PMID: 21542833 Free PMC article.

3

Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization.

Nixon M, Wake DJ, Livingstone DE, Stimson RH, Esteves CL, Seckl JR, Chapman KE, Andrew R, Walker BR. Nixon M, et al. Diabetes. 2012 Apr;61(4):790-6. doi: 10.2337/db11-0931. Epub 2012 Feb 22. Diabetes. 2012. PMID: 22357964 Free PMC article. Clinical Trial.

4

Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation.

Ramage LE, Akyol M, Fletcher AM, Forsythe J, Nixon M, Carter RN, van Beek EJ, Morton NM, Walker BR, Stimson RH. Ramage LE, et al. Among authors: nixon m. Cell Metab. 2016 Jul 12;24(1):130-41. doi: 10.1016/j.cmet.2016.06.011. Cell Metab. 2016. PMID: 27411014 Free PMC article. Clinical Trial.

5

ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.

Nixon M, Mackenzie SD, Taylor AI, Homer NZ, Livingstone DE, Mouras R, Morgan RA, Mole DJ, Stimson RH, Reynolds RM, Elfick AP, Andrew R, Walker BR. Nixon M, et al. Sci Transl Med. 2016 Aug 17;8(352):352ra109. doi: 10.1126/scitranslmed.aaf9074. Sci Transl Med. 2016. PMID: 27535620

6

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.

Morgan RA, Beck KR, Nixon M, Homer NZM, Crawford AA, Melchers D, Houtman R, Meijer OC, Stomby A, Anderson AJ, Upreti R, Stimson RH, Olsson T, Michoel T, Cohain A, Ruusalepp A, Schadt EE, Björkegren JLM, Andrew R, Kenyon CJ, Hadoke PWF, Odermatt A, Keen JA, Walker BR. Morgan RA, et al. Among authors: nixon m. Sci Rep. 2017 Sep 6;7(1):10633. doi: 10.1038/s41598-017-10410-1. Sci Rep. 2017. PMID: 28878267 Free PMC article.

7

Dysregulation of Cortisol Metabolism in Equine Pituitary Pars Intermedia Dysfunction.

Morgan RA, Keen JA, Homer N, Nixon M, McKinnon-Garvin AM, Moses-Williams JA, Davis SR, Hadoke PWF, Walker BR. Morgan RA, et al. Among authors: nixon m. Endocrinology. 2018 Nov 1;159(11):3791-3800. doi: 10.1210/en.2018-00726. Endocrinology. 2018. PMID: 30289445 Free PMC article.

8

Androgens modulate glucocorticoid receptor activity in adipose tissue and liver.

Spaanderman DCE, Nixon M, Buurstede JC, Sips HC, Schilperoort M, Kuipers EN, Backer EA, Kooijman S, Rensen PCN, Homer NZM, Walker BR, Meijer OC, Kroon J. Spaanderman DCE, et al. Among authors: nixon m. J Endocrinol. 2018 Oct 1:JOE-18-0503.R1. doi: 10.1530/JOE-18-0503. Online ahead of print. J Endocrinol. 2018. PMID: 30400038

9

Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice.

Mak TCS, Livingstone DEW, Nixon M, Walker BR, Andrew R. Mak TCS, et al. Among authors: nixon m. Endocrinology. 2019 Sep 1;160(9):2061-2073. doi: 10.1210/en.2019-00236. Endocrinology. 2019. PMID: 31199473 Free PMC article.

10

Quantitative analysis of 11-dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography/triple quadrupole mass spectrometry.

Verma M, Sooy K, Just G, Nixon M, Morgan R, Andrew R, Chapman KE, Homer NZM. Verma M, et al. Among authors: nixon m. Rapid Commun Mass Spectrom. 2020 Sep;34 Suppl 4(Suppl 4):e8610. doi: 10.1002/rcm.8610. Epub 2020 Feb 11. Rapid Commun Mass Spectrom. 2020. PMID: 31677354 Free PMC article.

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