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The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development.
Sakaki-Yumoto M, Kobayashi C, Sato A, Fujimura S, Matsumoto Y, Takasato M, Kodama T, Aburatani H, Asashima M, Yoshida N, Nishinakamura R. Sakaki-Yumoto M, et al. Among authors: nishinakamura r. Development. 2006 Aug;133(15):3005-13. doi: 10.1242/dev.02457. Epub 2006 Jun 21. Development. 2006. PMID: 16790473
Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.
Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H. Oikawa T, et al. Among authors: nishinakamura r. Gastroenterology. 2009 Mar;136(3):1000-11. doi: 10.1053/j.gastro.2008.11.018. Epub 2008 Nov 8. Gastroenterology. 2009. PMID: 19185577
Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT.
Kaku Y, Ohmori T, Kudo K, Fujimura S, Suzuki K, Evans SM, Kawakami Y, Nishinakamura R. Kaku Y, et al. Among authors: nishinakamura r. J Am Soc Nephrol. 2013 Jul;24(8):1242-9. doi: 10.1681/ASN.2012050528. Epub 2013 May 2. J Am Soc Nephrol. 2013. PMID: 23641053 Free PMC article.
148 results