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Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism.
Nishimoto K, Koga M, Seki T, Oki K, Gomez-Sanchez EP, Gomez-Sanchez CE, Naruse M, Sakaguchi T, Morita S, Kosaka T, Oya M, Ogishima T, Yasuda M, Suematsu M, Kabe Y, Omura M, Nishikawa T, Mukai K. Nishimoto K, et al. Mol Cell Endocrinol. 2017 Feb 5;441:124-133. doi: 10.1016/j.mce.2016.10.014. Epub 2016 Oct 14. Mol Cell Endocrinol. 2017. PMID: 27751767 Free PMC article. Review.
Adrenocortical zonation in humans under normal and pathological conditions.
Nishimoto K, Nakagawa K, Li D, Kosaka T, Oya M, Mikami S, Shibata H, Itoh H, Mitani F, Yamazaki T, Ogishima T, Suematsu M, Mukai K. Nishimoto K, et al. J Clin Endocrinol Metab. 2010 May;95(5):2296-305. doi: 10.1210/jc.2009-2010. Epub 2010 Mar 3. J Clin Endocrinol Metab. 2010. PMID: 20200334
Histopathological diagnosis of primary aldosteronism using CYP11B2 immunohistochemistry.
Nanba K, Tsuiki M, Sawai K, Mukai K, Nishimoto K, Usui T, Tagami T, Okuno H, Yamamoto T, Shimatsu A, Katabami T, Okumura A, Kawa G, Tanabe A, Naruse M. Nanba K, et al. Among authors: nishimoto k. J Clin Endocrinol Metab. 2013 Apr;98(4):1567-74. doi: 10.1210/jc.2012-3726. Epub 2013 Feb 26. J Clin Endocrinol Metab. 2013. PMID: 23443813
Adrenal nodularity and somatic mutations in primary aldosteronism: one node is the culprit?
Dekkers T, ter Meer M, Lenders JW, Hermus AR, Schultze Kool L, Langenhuijsen JF, Nishimoto K, Ogishima T, Mukai K, Azizan EA, Tops B, Deinum J, Küsters B. Dekkers T, et al. Among authors: nishimoto k. J Clin Endocrinol Metab. 2014 Jul;99(7):E1341-51. doi: 10.1210/jc.2013-4255. Epub 2014 Apr 23. J Clin Endocrinol Metab. 2014. PMID: 24758183
Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands.
Nishimoto K, Tomlins SA, Kuick R, Cani AK, Giordano TJ, Hovelson DH, Liu CJ, Sanjanwala AR, Edwards MA, Gomez-Sanchez CE, Nanba K, Rainey WE. Nishimoto K, et al. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4591-9. doi: 10.1073/pnas.1505529112. Epub 2015 Aug 3. Proc Natl Acad Sci U S A. 2015. PMID: 26240369 Free PMC article.
533 results