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Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut.
Infect Immun. 2013 Feb;81(2):478-86. doi: 10.1128/IAI.00453-12. Epub 2012 Dec 3.
Infect Immun. 2013.
PMID: 23208603
Free PMC article.
The Vi capsular polysaccharide prevents complement receptor 3-mediated clearance of Salmonella enterica serotype Typhi.
Wilson RP, Winter SE, Spees AM, Winter MG, Nishimori JH, Sanchez JF, Nuccio SP, Crawford RW, Tükel Ç, Bäumler AJ.
Wilson RP, et al. Among authors: nishimori jh.
Infect Immun. 2011 Feb;79(2):830-7. doi: 10.1128/IAI.00961-10. Epub 2010 Nov 22.
Infect Immun. 2011.
PMID: 21098104
Free PMC article.
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Microbial amyloids induce interleukin 17A (IL-17A) and IL-22 responses via Toll-like receptor 2 activation in the intestinal mucosa.
Nishimori JH, Newman TN, Oppong GO, Rapsinski GJ, Yen JH, Biesecker SG, Wilson RP, Butler BP, Winter MG, Tsolis RM, Ganea D, Tükel Ç.
Nishimori JH, et al.
Infect Immun. 2012 Dec;80(12):4398-408. doi: 10.1128/IAI.00911-12. Epub 2012 Oct 1.
Infect Immun. 2012.
PMID: 23027540
Free PMC article.
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Responses to amyloids of microbial and host origin are mediated through toll-like receptor 2.
Tükel C, Wilson RP, Nishimori JH, Pezeshki M, Chromy BA, Bäumler AJ.
Tükel C, et al. Among authors: nishimori jh.
Cell Host Microbe. 2009 Jul 23;6(1):45-53. doi: 10.1016/j.chom.2009.05.020.
Cell Host Microbe. 2009.
PMID: 19616765
Free PMC article.
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Toll-like receptors 1 and 2 cooperatively mediate immune responses to curli, a common amyloid from enterobacterial biofilms.
Tükel C, Nishimori JH, Wilson RP, Winter MG, Keestra AM, van Putten JP, Bäumler AJ.
Tükel C, et al. Among authors: nishimori jh.
Cell Microbiol. 2010 Oct;12(10):1495-505. doi: 10.1111/j.1462-5822.2010.01485.x.
Cell Microbiol. 2010.
PMID: 20497180
Free PMC article.
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