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Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis.
Yoshida G, Kawabata T, Takamatsu H, Saita S, Nakamura S, Nishikawa K, Fujiwara M, Enokidani Y, Yamamuro T, Tabata K, Hamasaki M, Ishii M, Kumanogoh A, Yoshimori T. Yoshida G, et al. Among authors: nishikawa k. Autophagy. 2022 Oct;18(10):2323-2332. doi: 10.1080/15548627.2021.2017587. Epub 2022 Jan 13. Autophagy. 2022. PMID: 35025696 Free PMC article.
Intercellular Communication between Keratinocytes and Fibroblasts Induces Local Osteoclast Differentiation: a Mechanism Underlying Cholesteatoma-Induced Bone Destruction.
Iwamoto Y, Nishikawa K, Imai R, Furuya M, Uenaka M, Ohta Y, Morihana T, Itoi-Ochi S, Penninger JM, Katayama I, Inohara H, Ishii M. Iwamoto Y, et al. Among authors: nishikawa k. Mol Cell Biol. 2016 May 16;36(11):1610-20. doi: 10.1128/MCB.01028-15. Print 2016 Jun 1. Mol Cell Biol. 2016. PMID: 27001307 Free PMC article.
Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation.
Baba M, Endoh M, Ma W, Toyama H, Hirayama A, Nishikawa K, Takubo K, Hano H, Hasumi H, Umemoto T, Hashimoto M, Irie N, Esumi C, Kataoka M, Nakagata N, Soga T, Yao M, Kamba T, Minami T, Ishii M, Suda T. Baba M, et al. Among authors: nishikawa k. J Bone Miner Res. 2018 Oct;33(10):1785-1798. doi: 10.1002/jbmr.3477. Epub 2018 Jun 26. J Bone Miner Res. 2018. PMID: 29893999 Free PMC article.
SLPI is a critical mediator that controls PTH-induced bone formation.
Morimoto A, Kikuta J, Nishikawa K, Sudo T, Uenaka M, Furuya M, Hasegawa T, Hashimoto K, Tsukazaki H, Seno S, Nakamura A, Okuzaki D, Sugihara F, Ninomiya A, Yoshimura T, Takao-Kawabata R, Matsuda H, Ishii M. Morimoto A, et al. Among authors: nishikawa k. Nat Commun. 2021 Apr 9;12(1):2136. doi: 10.1038/s41467-021-22402-x. Nat Commun. 2021. PMID: 33837198 Free PMC article.
Osteoclasts adapt to physioxia perturbation through DNA demethylation.
Nishikawa K, Seno S, Yoshihara T, Narazaki A, Sugiura Y, Shimizu R, Kikuta J, Sakaguchi R, Suzuki N, Takeda N, Semba H, Yamamoto M, Okuzaki D, Motooka D, Kobayashi Y, Suematsu M, Koseki H, Matsuda H, Yamamoto M, Tobita S, Mori Y, Ishii M. Nishikawa K, et al. EMBO Rep. 2021 Dec 6;22(12):e53035. doi: 10.15252/embr.202153035. Epub 2021 Oct 18. EMBO Rep. 2021. PMID: 34661337 Free PMC article.
2,241 results