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Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme.
Nishi E, Hiraoka Y, Yoshida K, Okawa K, Kita T. Nishi E, et al. J Biol Chem. 2006 Oct 13;281(41):31164-72. doi: 10.1074/jbc.M601316200. Epub 2006 Aug 21. J Biol Chem. 2006. PMID: 16923819 Free article.
We have recently identified nardilysin (N-arginine dibasic convertase (NRDc)), a metalloendopeptidase of the M16 family, as a protein that specifically binds HB-EGF (Nishi, E., Prat, A., Hospital, V., Elenius, K., and Klagsbrun, M. (2001) EMBO J. 20, 3342-3350). ...
We have recently identified nardilysin (N-arginine dibasic convertase (NRDc)), a metalloendopeptidase of the M16 family, as a protein that s …
Clopidogrel resistance in Japanese patients scheduled for percutaneous coronary intervention.
Hoshino K, Horiuchi H, Tada T, Tazaki J, Nishi E, Kawato M, Ikeda T, Yamamoto H, Akao M, Furukawa Y, Shizuta S, Toma M, Tamura T, Saito N, Doi T, Ozasa N, Jinnai T, Takahashi K, Watanabe H, Yoshikawa Y, Nishimoto N, Ouchi C, Morimoto T, Kita T, Kimura T. Hoshino K, et al. Among authors: nishi e. Circ J. 2009 Feb;73(2):336-42. doi: 10.1253/circj.cj-08-0559. Epub 2008 Dec 24. Circ J. 2009. PMID: 19106460 Free article. Clinical Trial.
Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α.
Kanda K, Komekado H, Sawabu T, Ishizu S, Nakanishi Y, Nakatsuji M, Akitake-Kawano R, Ohno M, Hiraoka Y, Kawada M, Kawada K, Sakai Y, Matsumoto K, Kunichika M, Kimura T, Seno H, Nishi E, Chiba T. Kanda K, et al. Among authors: nishi e. EMBO Mol Med. 2012 May;4(5):396-411. doi: 10.1002/emmm.201200216. Epub 2012 Feb 20. EMBO Mol Med. 2012. PMID: 22351606 Free PMC article.
Critical roles of nardilysin in the maintenance of body temperature homoeostasis.
Hiraoka Y, Matsuoka T, Ohno M, Nakamura K, Saijo S, Matsumura S, Nishi K, Sakamoto J, Chen PM, Inoue K, Fushiki T, Kita T, Kimura T, Nishi E. Hiraoka Y, et al. Among authors: nishi e, nishi k. Nat Commun. 2014;5:3224. doi: 10.1038/ncomms4224. Nat Commun. 2014. PMID: 24492630 Free PMC article.
197 results