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BET bromodomain inhibitors synergize with ATR inhibitors in melanoma.
Veppil Muralidharan S, Osk Einarsdottir B, Bhadury J, Lindberg MF, Wu J, Campeau E, Olofsson Bagge R, Stierner U, Ny L, Nilsson LM, Nilsson JA. Veppil Muralidharan S, et al. Among authors: nilsson ja, nilsson lm. Cell Death Dis. 2017 Dec 14;8(12):e3177. doi: 10.1038/cddis.2017.557. Cell Death Dis. 2017. PMID: 29240074 Free PMC article.
BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma.
Bhadury J, Nilsson LM, Muralidharan SV, Green LC, Li Z, Gesner EM, Hansen HC, Keller UB, McLure KG, Nilsson JA. Bhadury J, et al. Among authors: nilsson ja, nilsson lm. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):E2721-30. doi: 10.1073/pnas.1406722111. Epub 2014 Jun 16. Proc Natl Acad Sci U S A. 2014. PMID: 24979794 Free PMC article.
Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions.
Einarsdottir BO, Bagge RO, Bhadury J, Jespersen H, Mattsson J, Nilsson LM, Truvé K, López MD, Naredi P, Nilsson O, Stierner U, Ny L, Nilsson JA. Einarsdottir BO, et al. Among authors: nilsson ja, nilsson o, nilsson lm. Oncotarget. 2014 Oct 30;5(20):9609-18. doi: 10.18632/oncotarget.2445. Oncotarget. 2014. PMID: 25228592 Free PMC article.
BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.
Lunavat TR, Cheng L, Einarsdottir BO, Olofsson Bagge R, Veppil Muralidharan S, Sharples RA, Lässer C, Gho YS, Hill AF, Nilsson JA, Lötvall J. Lunavat TR, et al. Among authors: nilsson ja. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5930-E5939. doi: 10.1073/pnas.1705206114. Epub 2017 Jul 6. Proc Natl Acad Sci U S A. 2017. PMID: 28684402 Free PMC article.
BET bromodomain inhibitors synergize with ATR inhibitors in melanoma.
Muralidharan SV, Einarsdottir BO, Bhadury J, Lindberg MF, Wu J, Campeau E, Bagge RO, Stierner U, Ny L, Nilsson LM, Nilsson JA. Muralidharan SV, et al. Among authors: nilsson ja, nilsson lm. Cell Death Dis. 2017 Aug 10;8(8):e2982. doi: 10.1038/cddis.2017.383. Cell Death Dis. 2017. PMID: 28796244 Free PMC article.
319 results