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Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation.
Bharath LP, Agrawal M, McCambridge G, Nicholas DA, Hasturk H, Liu J, Jiang K, Liu R, Guo Z, Deeney J, Apovian CM, Snyder-Cappione J, Hawk GS, Fleeman RM, Pihl RMF, Thompson K, Belkina AC, Cui L, Proctor EA, Kern PA, Nikolajczyk BS. Bharath LP, et al. Among authors: nikolajczyk bs. Cell Metab. 2020 Jul 7;32(1):44-55.e6. doi: 10.1016/j.cmet.2020.04.015. Epub 2020 May 12. Cell Metab. 2020. PMID: 32402267 Free PMC article.
B cells from periodontal disease patients express surface Toll-like receptor 4.
Shin H, Zhang Y, Jagannathan M, Hasturk H, Kantarci A, Liu H, Van Dyke TE, Ganley-Leal LM, Nikolajczyk BS. Shin H, et al. Among authors: nikolajczyk bs. J Leukoc Biol. 2009 Apr;85(4):648-55. doi: 10.1189/jlb.0708428. Epub 2008 Dec 31. J Leukoc Biol. 2009. PMID: 19118102 Free PMC article.
Toll-like receptors regulate B cell cytokine production in patients with diabetes.
Jagannathan M, McDonnell M, Liang Y, Hasturk H, Hetzel J, Rubin D, Kantarci A, Van Dyke TE, Ganley-Leal LM, Nikolajczyk BS. Jagannathan M, et al. Among authors: nikolajczyk bs. Diabetologia. 2010 Jul;53(7):1461-71. doi: 10.1007/s00125-010-1730-z. Epub 2010 Apr 11. Diabetologia. 2010. PMID: 20383694 Free PMC article.
When diet and exercise are not enough, think immunomodulation.
Snyder-Cappione JE, Nikolajczyk BS. Snyder-Cappione JE, et al. Among authors: nikolajczyk bs. Mol Aspects Med. 2013 Feb;34(1):30-8. doi: 10.1016/j.mam.2012.10.003. Epub 2012 Oct 16. Mol Aspects Med. 2013. PMID: 23078865 Review.
B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile.
DeFuria J, Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, Carr JD, Nersesova YR, Markham D, Strissel KJ, Watkins AA, Zhu M, Allen J, Bouchard J, Toraldo G, Jasuja R, Obin MS, McDonnell ME, Apovian C, Denis GV, Nikolajczyk BS. DeFuria J, et al. Among authors: nikolajczyk bs. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5133-8. doi: 10.1073/pnas.1215840110. Epub 2013 Mar 11. Proc Natl Acad Sci U S A. 2013. PMID: 23479618 Free PMC article. Clinical Trial.
77 results